Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11161035 | 0.90 | CYP3A4 (0.36) | CYP3A4ALDH1A1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL28977828 | 0.82 | CYP3A4 (0.39) | CYP3A4ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL284263 | 0.80 | TSHR (0.44) | CYP3A4ALDH1A1SMN1; SMN2TP53TSHR | |
| SCHEMBL2363793 | 0.78 | CYP3A4 (0.37) | CYP3A4ALDH1A1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL782365 | 0.78 | TSHR (0.39) | CYP3A4ALDH1A1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL8678916 | 0.78 | TSHR (0.39) | CYP3A4ALDH1A1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL2825649 | 0.77 | CYP3A4 (0.36) | CYP3A4ALDH1A1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL10556756 | 0.77 | CYP3A4 (0.36) | CYP3A4ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL22592255 | 0.76 | MAPT (0.40) | CYP3A4ALDH1A1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL9695816 | 0.75 | MEN1 (0.42) | CYP3A4ALDH1A1SMN1; SMN2MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181921-A1 | 2-5A ANALOGS AND THEIR METHODS OF USE | ALIOS BIOPHARMA INC. (US) | 2009-07-16 | — | — | US | disclosed |
| WO-2009086201-A1 | 2-5A ANALOGS AND THEIR USE AS ANTI-CANCER, ANTI-VIRAL AND ANTI- PARAS ITI C AGENTS | ALIOS BIOPHARMA, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| US-4394329-A | PLASTICIZING, EXPLOSIVES, VASODILATION, 2-HYDROXYMETHYL-1,3-PROPANEDIOL NITRATION | THIOKOL CORPORATION (US) | 1983-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181921-A1 | 2-5A ANALOGS AND THEIR METHODS OF USE | RNASEL, RNASE1, RNASEH1 | CYP3A4 1782/4885ALDH1A1 1161/4885SMN1; SMN2 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.