Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.51 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.50 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.50 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.50 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.50 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.50 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.50 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16118213 | 0.90 | LMNA (0.61) | ENPP2DGAT2LMNANPC1RAB9A | |
| SCHEMBL27975953 | 0.88 | LMNA (0.63) | ENPP2DGAT2LMNANPC1RAB9A | |
| SCHEMBL4305918 | 0.86 | CNR1 (0.45) | ENPP2DGAT2LMNANPC1RAB9A | |
| SCHEMBL4309070 | 0.86 | CNR1 (0.45) | ENPP2DGAT2LMNANPC1RAB9A | |
| SCHEMBL28467935 | 0.85 | HDAC3 (0.64) | LMNANPC1RAB9ASMN1; SMN2SOAT1 | |
| SCHEMBL29796263 | 0.85 | HDAC3 (0.64) | LMNANPC1RAB9ASMN1; SMN2SOAT1 | |
| SCHEMBL21597967 | 0.84 | ENPP2 (0.69) | ENPP2DGAT2LMNANPC1RAB9A | |
| SCHEMBL11304280 | 0.82 | ALDH1A1 (0.62) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9170867 | 0.82 | HDAC3 (0.55) | ENPP2DGAT2LMNANPC1RAB9A | |
| SCHEMBL28630398 | 0.82 | TOP2A (0.49) | LMNAPOLBHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |