Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21998679 | 0.97 | KDM4E (0.55) | KDM4ECNR1LMNANPC1RAB9A | |
| SCHEMBL21998921 | 0.97 | KDM4E (0.55) | KDM4ECNR1LMNANPC1RAB9A | |
| SCHEMBL21998903 | 0.97 | KDM4E (0.55) | KDM4ECNR1LMNANPC1RAB9A | |
| SCHEMBL4315463 | 0.92 | HDAC3 (0.55) | KDM4ECNR1LMNANPC1RAB9A | |
| SCHEMBL4310606 | 0.92 | HDAC3 (0.55) | KDM4ECNR1LMNANPC1RAB9A | |
| SCHEMBL4309070 | 0.89 | CNR1 (0.45) | KDM4ECNR1LMNANPC1RAB9A | |
| SCHEMBL4305918 | 0.89 | CNR1 (0.45) | KDM4ECNR1LMNANPC1RAB9A | |
| SCHEMBL10602139 | 0.89 | CNR1 (0.64) | KDM4ECNR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16118213 | 0.87 | LMNA (0.61) | CNR1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21998663 | 0.86 | ALDH1A1 (0.67) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |