Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23829734 | 0.83 | MEN1 (0.42) | PARP1CYP3A4SMN1; SMN2MAPTTSHR | |
| SCHEMBL27543552 | 0.77 | PARP1 (0.45) | PARP1CYP3A4SMN1; SMN2MAPTTSHR | |
| SCHEMBL6511630 | 0.77 | CYP3A4 (0.40) | PARP1CYP3A4SMN1; SMN2MAPTTSHR | |
| SCHEMBL6027899 | 0.77 | KDM4E (0.43) | PARP1MAPTTSHRHSD17B10KDM4E | |
| SCHEMBL813450 | 0.76 | PARP1 (0.53) | PARP1CYP3A4SMN1; SMN2MAPTTSHR | |
| SCHEMBL2139 | 0.76 | KDM4E (0.59) | PARP1SMN1; SMN2MAPTHSD17B10KDM4E | |
| SCHEMBL6514540 | 0.75 | CYP3A4 (0.39) | PARP1CYP3A4SMN1; SMN2MAPTTSHR | |
| SCHEMBL6523892 | 0.75 | CYP3A4 (0.39) | PARP1CYP3A4SMN1; SMN2MAPTTSHR | |
| SCHEMBL6520264 | 0.75 | CYP3A4 (0.39) | PARP1CYP3A4SMN1; SMN2MAPTTSHR | |
| SCHEMBL21984133 | 0.75 | PLAU (0.41) | SMN1; SMN2MAPTTSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051968-B1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | UNIV CALIFORNIA (US) | 2020-04-29 | — | — | EP | disclosed |
| US-8551453-B2 | Aromatic triamide-lanthanide complexes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-08 | — | — | US | disclosed |
| US-20090036537-A1 | AROMATIC TRIAMIDE-LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-02-05 | — | — | US | disclosed |
| EP-1706452-B1 | AROMATIC TRIAMIDE-LANTHANIDE COMPLEXES | UNIV CALIFORNIA OFFICE OF THE (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1706452-A4 | AROMATIC TRIAMIDE-LANTHANIDE COMPLEXES | UNIV CALIFORNIA OFFICE OF THE (US) | 2007-01-10 | — | — | EP | disclosed |
| EP-1706452-A2 | AROMATIC TRIAMIDE-LANTHANIDE COMPLEXES | The Regents of the University of California, Office of the President (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2006001835-A2 | AROMATIC TRIAMIDE-LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036537-A1 | AROMATIC TRIAMIDE-LANTHANIDE COMPLEXES | TRPV5, TRPC5, TRPM5 | PARP1 1372/4885CYP3A4 3870/4885SMN1; SMN2 4746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.