Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 7/20 | 0.37 |
| ▸ | CTSB | P07858 | 5/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 3/20 | 0.31 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911546 | 0.84 | ALDH1A1 (0.42) | CAPN1CTSBALDH1A1CTSK | |
| SCHEMBL4302692 | 0.82 | CTSK (0.50) | CAPN1CTSBALDH1A1CTSK | |
| SCHEMBL2995716 | 0.80 | ALDH1A1 (0.50) | CAPN1CTSBALDH1A1CTSK | |
| SCHEMBL12219762 | 0.80 | ALDH1A1 (0.50) | CAPN1CTSBALDH1A1CTSK | |
| SCHEMBL7974645 | 0.80 | ALDH1A1 (0.50) | CAPN1CTSBALDH1A1CTSK | |
| Levacetylleucine SCHEMBL8572338 | 0.80 | ALDH1A1 (0.52) | FOLH1ALDH1A1CTSDBACE1 | |
| SCHEMBL5499048 | 0.80 | CTSK (0.48) | CAPN1CTSBALDH1A1CTSK | |
| SCHEMBL742876 | 0.78 | ALDH1A1 (0.41) | FOLH1ALDH1A1CTSKMETAP2METAP1 | |
| SCHEMBL1697387 | 0.78 | ALDH1A1 (0.41) | FOLH1ALDH1A1CTSKMETAP2METAP1 | |
| SCHEMBL18056660 | 0.76 | CAPN1 (0.35) | CAPN1CTSBFOLH1CTSKMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090317854-A1 | Recombinant adenylate cyclase of BORDETELLA SP. for diagnostic and immunomonitoring uses, method of diagnosing or immunomonitoring using said recombinant adenylate cyclase, and kit for diagnosing or immunomonitoring comprising said recombinant adenylate cyclase | Institut Pasteur, INSERM (Institut National De La Sante Et De La Recherche Medicale) | 2009-12-24 | — | — | US | disclosed |
| US-20060286613-A1 | Recombinant adenylate cyclase of Bordetella sp. for diagnostic and immunomonitoring uses, method of diagnosing or immunomonitoring using said recombinant adenylate cyclase, and kit for diagnosing or immunomonitoring comprising said recombinant adenylate cyclase | VETERINARY LABORATORIES AGENCY-WEYBRIDGE (GB) | 2006-12-21 | — | — | US | disclosed |
| EP-1716415-A1 | RECOMBINANT ADENYLATE CYCLASE OF BORDETELLA SP. FOR DIAGNOSTIC AND IMMUNOMONITORING USES, METHOD OF DIAGNOSING OR IMMUNOMONITORING USING SAID RECOMBINANT ADENYLATE CYCLASE, AND KIT FOR DIAGNOSING OR IMMUNOMONITORING COMPRISING SAID RECOMBINANT ADENYLATE CYCLASE | INSTITUT PASTEUR (FR) | 2006-11-02 | — | — | EP | disclosed |
| US-20060019323-A1 | Recombinant adenylate cyclase of Bordetella sp. for diagnostic and immunomonitoring uses, method of diagnosing or immunomonitoring using said recombinant adenylate cyclase, and kit for diagnosing or immunomonitoring comprising said recombinant adenylate cyclase | INSTITUT PASTEUR (FR) | 2006-01-26 | — | — | US | disclosed |
| WO-2005054851-A1 | RECOMBINANT ADENYLATE CYCLASE OF BORDETELLA SP. FOR DIAGNOSTIC AND IMMUNOMONITORING USES, METHOD OF DIAGNOSING OR IMMUNOMONITORING USING SAID RECOMBINANT ADENYLATE CYCLASE, AND KIT FOR DIAGNOSING OR IMMUNOMONITORING COMPRISING SAID RECOMBINANT ADENYLATE CYCLASE | INSTITUT PASTEUR (FR) | 2005-06-16 | — | — | WO | disclosed |