Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 7/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 5/20 | 0.34 |
| ▸ | CTSB | P07858 | 4/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995716 | 0.89 | ALDH1A1 (0.50) | ALDH1A1CAPN1CTSKCTSB | |
| SCHEMBL7974645 | 0.89 | ALDH1A1 (0.50) | ALDH1A1CAPN1CTSKCTSB | |
| SCHEMBL12219762 | 0.89 | ALDH1A1 (0.50) | ALDH1A1CAPN1CTSKCTSB | |
| SCHEMBL5499048 | 0.89 | CTSK (0.48) | ALDH1A1CAPN1CTSKCTSB | |
| SCHEMBL4302692 | 0.85 | CTSK (0.50) | ALDH1A1CAPN1CTSKCTSB | |
| SCHEMBL4307884 | 0.84 | CAPN1 (0.37) | ALDH1A1CAPN1CTSKCTSB | |
| SCHEMBL1988780 | 0.77 | — | — | |
| SCHEMBL7032277 | 0.77 | — | — | |
| SCHEMBL371255 | 0.77 | — | — | |
| SCHEMBL20375816 | 0.77 | PAX8 (0.47) | CAPN1CTSKSLC7A5LAP3CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6322962-B1 | MONITORING MODULATORS OF ENZYME ACTIVITY; DETECT CELL EXPRESSING PREFERENTIAL ACTIVITY, INCUBATE WITH MODULATOR, MONITOR CELL FOR ADJUSTMENT IN ENZYMATIC ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2001-11-27 | — | — | US | disclosed |
| WO-2000009677-A2 | STEROL-REGULATED SITE-1 PROTEASE AND ASSAYS OF MODULATORS THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-02-24 | — | — | WO | disclosed |