Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15754813 | 0.67 | ALDH1A1 (0.37) | KDM4EHPGDALDH1A1GAAKLK7 | |
| SCHEMBL10514874 | 0.67 | ALOX15 (0.46) | KDM4EHPGDALDH1A1GAAKLK7 | |
| SCHEMBL15754656 | 0.65 | NPC1 (0.33) | KDM4EALDH1A1PARP1 | |
| SCHEMBL484880 | 0.62 | PARP1 (0.37) | KDM4EHPGDALDH1A1GAAKLK7 | |
| SCHEMBL14249149 | 0.62 | GAA (0.35) | KDM4EHPGDALDH1A1GAAKLK7 | |
| SCHEMBL30220316 | 0.62 | KDM4E (0.40) | KDM4EHPGDALDH1A1GAAKLK7 | |
| SCHEMBL2008377 | 0.60 | LMNA (0.48) | KDM4EHPGDALDH1A1GAAKLK7 | |
| SCHEMBL2008375 | 0.60 | KDM4E (0.35) | KDM4EHPGDALDH1A1GAAKLK7 | |
| SCHEMBL27985193 | 0.60 | KDM4E (0.39) | KDM4EHPGDALDH1A1GAAKLK7 | |
| SCHEMBL25514677 | 0.59 | ALDH1A1 (0.50) | KDM4EHPGDALDH1A1CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834452-B2 | CXCR7 antagonists | CHEMOCENTRYX, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| CN-117069725-A | Imidazopyridazine substituted benzene ring derivative, preparation method, pharmaceutical composition and application | 上海赛默罗生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| US-20220127272-A1 | CXCR7 ANTAGONISTS | CHEMOCENTRYX, INC. | 2022-04-28 | — | — | US | disclosed |
| WO-2020113138-A1 | A SYSTEM FOR SEQUENCING BIOPOLYMERS | UNIVERSAL SEQUENCING TECHNOLOGY (US) | 2020-06-04 | — | — | WO | disclosed |
| WO-2009130231-A1 | PYRROLO [1, 2-A] PYRAZINE DERIVATIVES AS VASOPRESSIN VIB RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11834452-B2 | CXCR7 antagonists | CXCR1, CXCR5, CCR7 | KDM4E 4537/4885HPGD 379/4885ALDH1A1 1699/4885 |
| US-20220127272-A1 | CXCR7 ANTAGONISTS | CXCR1, CXCR5, CCR7 | KDM4E 4537/4885HPGD 379/4885ALDH1A1 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.