Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43088 | 1.00 | NOS2 (0.35) | NOS2NOS1 | |
| SCHEMBL7741526 | 0.88 | — | — | |
| SCHEMBL6996772 | 0.82 | — | — | |
| SCHEMBL19595018 | 0.82 | — | — | |
| SCHEMBL3935708 | 0.82 | — | — | |
| SCHEMBL7739920 | 0.79 | NOS1 (0.35) | NOS2NOS1 | |
| SCHEMBL3932444 | 0.77 | — | — | |
| SCHEMBL397148 | 0.77 | — | — | |
| SCHEMBL7192856 | 0.77 | NOS1 (0.34) | NOS2NOS1 | |
| SCHEMBL7192859 | 0.77 | NOS1 (0.34) | NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102089277-B | Cyclic amine-1-carboxylic acid ester derivative and pharmaceutical composition containing same | DAINIPPON SUMITOMO PHARMA CO | 2014-02-12 | — | — | CN | disclosed |
| EP-2484664-B1 | Cyclic amine-1-carboxylic acid ester derivative and pharmaceutical composition containing the same | DAINIPPON SUMITOMO PHARMA CO (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-8367835-B2 | Cyclic amine-1-carboxylic acid ester derivative and pharmaceutical composition containing the same | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| EP-2484664-A1 | Cyclic amine-1-carboxylic acid ester derivative and pharmaceutical composition containing the same | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-08-08 | — | — | EP | disclosed |
| US-20120028937-A1 | CYCLIC AMINE-1-CARBOXYLIC ACID ESTER DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
| CN-102089277-A | Cyclic amine-1-carboxylic acid ester derivative and pharmaceutical composition containing the same | DAINIPPON SUMITOMO PHARMA CO | 2011-06-08 | — | — | CN | disclosed |
| EP-2277861-A1 | CYCLIC AMINE-1-CARBOXYLIC ACID ESTER DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2011-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028937-A1 | CYCLIC AMINE-1-CARBOXYLIC ACID ESTER DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | HRH3, ARG1, CNR1 | NOS2 179/4885NOS1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.