SCHEMBL4309173

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4309717	0.91	MGLL (0.46)	MGLLKMT2AMEN1
	SCHEMBL4318842	0.91	MGLL (0.42)	MGLLPOLBALDH1A1HSD11B1KMT2A
	SCHEMBL4310209	0.90	HSD11B1 (0.48)	MGLLPOLBALDH1A1SMN1; SMN2HSD11B1
	SCHEMBL4314273	0.88	SMN1; SMN2 (0.45)	MGLLPOLBALDH1A1LMNASMN1; SMN2
	SCHEMBL4312834	0.83	CYP3A4 (0.39)	ALDH1A1SMN1; SMN2KMT2ACYP2C9CYP2C19
	SCHEMBL4311381	0.82	POLB (0.39)	MGLLPOLBLMNACYP2C9CYP2C19
	SCHEMBL4315951	0.82	POLB (0.37)	MGLLPOLBCYP2C9CYP2C19CYP3A4
	SCHEMBL4316498	0.81	HSD11B1 (0.46)	MGLLPOLBSMN1; SMN2HSD11B1GAA
	SCHEMBL4311892	0.81	HSD11B1 (0.46)	MGLLPOLBALDH1A1SMN1; SMN2HSD11B1
	SCHEMBL4313590	0.81	POLB (0.37)	POLBKMT2AGAACHRM2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.