SCHEMBL4309389

SCHEMBL4309389

CN1C(=O)NC2(OC(CO)C(O)C(O)C2O)C1=O

nearest known ligand 0.71

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PYGB P11216 8/20 0.71
PYGL P06737 3/20 0.57
PYGM P11217 2/20 0.57
LMNA P02545 1/20 0.34
GBA1 P04062 1/20 0.34
ADSS2 P30520 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4314468 0.83 PYGB (1.00) PYGBPYGLPYGMLMNAGBA1
SCHEMBL4313854 0.82 PYGB (1.00) PYGBPYGLPYGMLMNAGBA1
SCHEMBL4316291 0.78 PYGB (0.61) PYGBPYGLPYGM
SCHEMBL29941045 0.73 PYGB (1.00) PYGBPYGLPYGMLMNAGBA1
SCHEMBL4330413 0.71 PYGB (1.00) PYGBPYGLPYGMLMNAGBA1
Hydantocidin SCHEMBL10339110 0.68 PYGB (0.90) PYGBPYGLPYGMLMNAGBA1
Hydantocidin SCHEMBL8074132 0.68 PYGB (0.90) PYGBPYGLPYGMLMNAGBA1
Hydantocidin SCHEMBL8072284 0.68 PYGB (0.90) PYGBPYGLPYGMLMNAGBA1
SCHEMBL3714856 0.64 PYGB (0.46) PYGBPYGLPYGMLMNAGBA1
SCHEMBL24924778 0.63 PYGB (0.44) PYGBPYGLPYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed