SCHEMBL4330413

SCHEMBL4330413

O=C1NC(=S)NC12OC(CO)C(O)C(O)C2O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PYGB P11216 7/20 1.00
▸ PYGL P06737 3/20 1.00
▸ PYGM P11217 2/20 1.00
▸ AMY1A P0DUB6 1/20 0.42
▸ ADSS2 P30520 1/20 0.42
▸ LMNA P02545 1/20 0.35
▸ GBA1 P04062 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29941045 0.84 PYGB (1.00) PYGBPYGLPYGMADSS2LMNA
Hydantocidin SCHEMBL8072284 0.79 PYGB (0.90) PYGBPYGLPYGMADSS2LMNA
Hydantocidin SCHEMBL8074132 0.79 PYGB (0.90) PYGBPYGLPYGMADSS2LMNA
Hydantocidin SCHEMBL10339110 0.79 PYGB (0.90) PYGBPYGLPYGMADSS2LMNA
SCHEMBL4314468 0.72 PYGB (1.00) PYGBPYGLPYGMADSS2LMNA
SCHEMBL4309389 0.71 PYGB (0.71) PYGBPYGLPYGMADSS2LMNA
SCHEMBL4313854 0.71 PYGB (1.00) PYGBPYGLPYGMADSS2LMNA
SCHEMBL7052003 0.63 PYGB (0.47) PYGBPYGLPYGMLMNAGBA1
SCHEMBL3712330 0.63 PYGB (0.47) PYGBPYGLPYGMLMNAGBA1
SCHEMBL3712328 0.63 PYGB (0.47) PYGBPYGLPYGMLMNAGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 — — EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 — — US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 — — US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 — — US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 — — US disclosed
EP-3681504-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE Icagen, Inc. (US) 2020-07-22 — — EP disclosed
WO-2019055754-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN, INC. (US) 2019-03-21 — — WO disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 — — US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 — — EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 — — EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 — — EP disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 — — EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 — — WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 — — US disclosed
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