⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933680 | 0.68 | — | — | |
| SCHEMBL11633170 | 0.67 | — | — | |
| SCHEMBL9795348 | 0.62 | — | — | |
| SCHEMBL3630395 | 0.62 | — | — | |
| SCHEMBL31051471 | 0.62 | — | — | |
| SCHEMBL2905139 | 0.60 | — | — | |
| SCHEMBL24201630 | 0.59 | HCAR2 (0.38) | — | |
| SCHEMBL29351819 | 0.57 | ALDH1A1 (0.52) | — | |
| SCHEMBL22245644 | 0.57 | — | — | |
| SCHEMBL6771 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10265464-A | — | — | None | — | — | JP | disclosed |
| US-20240315246-A1 | METHOD OF USING SIMAZINE FOR CONTROLLING ANNUAL BLUEGRASS IN COOL SEASON-TURFGRASSES | HOWARD HAROLD F (US) | 2024-09-26 | — | — | US | disclosed |
| WO-2024197286-A1 | A METHOD OF USING SIMAZINE FOR CONTROLLING ANNUAL BLUEGRASS IN COOL-SEASON TURFGRASSES | HOWARD HAROLD F (US) | 2024-09-26 | — | — | WO | disclosed |
| EP-1871765-B1 | 3-(INDAZOL-5-YL)-(1,2,4)TRIAZINE DERIVATIVES AND RELATED COMPOUNDS AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | SCHERING CORP (US) | 2009-12-09 | — | — | EP | disclosed |
| US-7528132-B2 | immunodeficiencies, cancers, cardiovascular diseases, endocrine disorders, Parkinson's disease, metabolic diseases, tumorigenesis, Alzheimer's disease, heart disease, diabetes, neurodegeneration, inflammation, kidney disease, atherosclerosis and airway disease; indazolyl [1,2,4]triazine compounds | SCHERING CORPORATION (US) | 2009-05-05 | — | — | US | disclosed |
| US-20080004257-A1 | Kinase inhibitors | SCHERING CORPORATION | 2008-01-03 | — | — | US | disclosed |
| EP-1871765-A2 | 3-(INDAZOL-5-YL)-(1,2,4)TRIAZINE DERIVATIVES AND RELATED COMPOUNDS AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | SCHERING CORPORATION (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006081230-A2 | 3-(INDAZOL-5-YL)-(1,2, 4) TRIAZINE DERIVATIVES AND RELATED COMPOUNDS AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | SCHERING CORPORATION (US) | 2006-08-03 | — | — | WO | disclosed |
| US-6159974-A | LDL receptor gene expression promoters | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-12-12 | — | — | US | disclosed |
| JP-H10265464-A | EXPRESSION ENHANCER OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUT CO LTD | 1998-10-06 | — | — | JP | disclosed |