SCHEMBL4310477

SCHEMBL4310477

C[C@]12CC[C@H]3[C@@H](CC=C4C[C@H](O)C=C[C@@]43C)[C@@H]1C[C@H](F)[C@@H]2N

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.42
ESR1 P03372 3/20 0.38
AR P10275 3/20 0.38
ESR2 Q92731 3/20 0.38
SHBG P04278 1/20 0.38
SERPINA6 P08185 1/20 0.38
CYP17A1 P05093 9/20 0.37
TBXAS1 P24557 1/20 0.36
SRD5A2 P31213 1/20 0.36
SIGMAR1 Q99720 2/20 0.36
MEN1 O00255 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
EBP Q15125 1/20 0.36
ALDH1A1 P00352 1/20 0.36
NR3C1 P04150 1/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP19A1 P11511 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1418907 1.00 L3MBTL1 (0.42) L3MBTL1ESR1ARESR2SHBG
SCHEMBL4305112 1.00 L3MBTL1 (0.42) L3MBTL1ESR1ARESR2SHBG
SCHEMBL1418909 1.00 L3MBTL1 (0.42) L3MBTL1ESR1ARESR2SHBG
SCHEMBL511011 0.90 ESR1 (0.40) L3MBTL1ESR1ARESR2SHBG
SCHEMBL511726 0.90 ESR1 (0.40) L3MBTL1ESR1ARESR2SHBG
SCHEMBL511010 0.90 ESR1 (0.40) L3MBTL1ESR1ARESR2SHBG
SCHEMBL1418591 0.90 ESR1 (0.40) L3MBTL1ESR1ARESR2SHBG
SCHEMBL512238 0.89 L3MBTL1 (0.43) L3MBTL1ESR1ARESR2SHBG
SCHEMBL512304 0.89 L3MBTL1 (0.43) L3MBTL1ESR1ARESR2SHBG
SCHEMBL512239 0.89 L3MBTL1 (0.43) L3MBTL1ESR1ARESR2SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7547687-B2 Therapeutic treatment methods HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2009-06-16 US disclosed
US-7482334-B2 Therapeutic treatment methods HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2009-01-27 US disclosed
US-20070275938-A1 Therapeutic Treatment Methods BIOVIE INC. 2007-11-29 US disclosed
US-20070275937-A1 Therapeutic Treatment Methods BIOVIE INC. 2007-11-29 US disclosed
US-20050101581-A1 Therapeutic treatment methods 2 BIOVIE INC. 2005-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070275938-A1 Therapeutic Treatment Methods HSD3B1, HSD3B2, HSD17B1 L3MBTL1 3940/4885ESR1 220/4885AR 262/4885
US-20070275937-A1 Therapeutic Treatment Methods HSD3B1, HSD3B2, HSD17B1 L3MBTL1 3940/4885ESR1 220/4885AR 262/4885
US-20050101581-A1 Therapeutic treatment methods 2 HSD3B2, HSD3B1, HSD17B2 L3MBTL1 3929/4885ESR1 259/4885AR 379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.