Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138869 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GPR35HIF1ASIRT6PDE7A | |
| SCHEMBL8147133 | 0.85 | ALDH1A1 (0.58) | ALDH1A1GPR35HIF1APDE7ATSHR | |
| SCHEMBL1999857 | 0.84 | PDE7A (0.54) | ALDH1A1HIF1APDE7AARTSHR | |
| SCHEMBL3207733 | 0.82 | AR (0.53) | ALDH1A1PDE7AARCYP3A4TDP1 | |
| SCHEMBL1532376 | 0.81 | FFAR4 (0.60) | ALDH1A1HIF1APDE7ACYP3A4TSHR | |
| SCHEMBL85544 | 0.81 | ALDH1A1 (0.58) | ALDH1A1HIF1APDE7AARTSHR | |
| SCHEMBL3965308 | 0.81 | PDE7A (0.51) | ALDH1A1HIF1APDE7AARTSHR | |
| Water SCHEMBL27993079 | 0.81 | AR (0.52) | ALDH1A1PDE7AARCYP3A4TDP1 | |
| SCHEMBL1998640 | 0.81 | CYP3A4 (0.52) | ALDH1A1HIF1ASIRT6ARCYP3A4 | |
| SCHEMBL29788520 | 0.81 | ATM (0.60) | ALDH1A1SIRT6ARCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253024-A1 | Nitro-Compound Cathodes for Batteries and Semi-Fuel Cells | NANOMATERIALS DISCOVERY CORPORATION | 2009-10-08 | — | — | US | claimed |
| US-20090253024-A1 | Nitro-Compound Cathodes for Batteries and Semi-Fuel Cells | NANOMATERIALS DISCOVERY CORPORATION | 2009-10-08 | — | — | US | disclosed |
| US-20090226368-A1 | Androgen-Receptor (AR) Ligands for Use in the Treatment and Diagnosis of AR-Related Pathologies | MEDICAL RESEARCH FUND AT THE TEL AVIV SOURASKY MEDICAL CENTER (IL) | 2009-09-10 | — | — | US | disclosed |
| WO-2007057909-A1 | ANDROGEN-RECEPTOR (AR) LIGANDS FOR USE IN THE TREATMENT AND DIAGNOSIS OF AR-RELATED PATHOLOGIES | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD. (IL) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226368-A1 | Androgen-Receptor (AR) Ligands for Use in the Treatment and Diagnosis of AR-Related Pathologies | AR, SHBG, ESRRB | ALDH1A1 432/4885GPR35 69/4885HIF1A 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.