SCHEMBL1532376

SCHEMBL1532376

Nc1ccc([N+](=O)[O-])cc1C(F)(F)F

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.60
PDE7A Q13946 1/20 0.59
TDP1 Q9NUW8 4/20 0.55
ALDH1A1 P00352 7/20 0.53
CYP3A4 P08684 3/20 0.53
POLB P06746 1/20 0.52
TSHR P16473 2/20 0.52
GAA P10253 1/20 0.52
THRB P10828 1/20 0.52
HTT P42858 1/20 0.49
ALOX15 P16050 1/20 0.47
HIF1A Q16665 1/20 0.44
LMNA P02545 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA5A P35218 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5900417 0.87 FFAR4 (0.50) FFAR4PDE7ATDP1ALDH1A1CYP3A4
SCHEMBL2594596 0.87 CYP3A4 (0.55) FFAR4PDE7ATDP1ALDH1A1CYP3A4
SCHEMBL30092967 0.87 CYP3A4 (0.55) FFAR4PDE7ATDP1ALDH1A1CYP3A4
SCHEMBL15325685 0.85 TDP1 (0.52) FFAR4PDE7ATDP1ALDH1A1CYP3A4
SCHEMBL1999857 0.84 PDE7A (0.54) FFAR4PDE7ATDP1ALDH1A1POLB
SCHEMBL3207733 0.82 AR (0.53) PDE7ATDP1ALDH1A1CYP3A4POLB
SCHEMBL11597414 0.82 TDP1 (0.49) FFAR4PDE7ATDP1ALDH1A1CYP3A4
SCHEMBL10938779 0.81 POLB (0.65) FFAR4PDE7ATDP1ALDH1A1CYP3A4
SCHEMBL30369258 0.81 POLB (0.65) FFAR4PDE7ATDP1ALDH1A1CYP3A4
SCHEMBL85544 0.81 ALDH1A1 (0.58) FFAR4PDE7ATDP1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115663403-B High-flame-retardance diaphragm for lithium ion battery and preparation process of high-flame-retardance diaphragm 江苏厚生新能源科技股份有限公司 2025-06-24 CN claimed
CN-118978846-B Composite coating and preparation method thereof 苏州奥利得精密模塑有限公司 2025-05-13 CN claimed
CN-114106341-B Comb copolymer, preparation method and application thereof 广州立邦涂料有限公司 2025-05-02 CN claimed
CN-118978846-A Composite coating and preparation method thereof 宁夏嘉铂睿环保科技集团有限公司 2024-11-19 CN claimed
CN-112724349-B Polymer and use thereof 立邦涂料(中国)有限公司 2024-07-05 CN claimed
CN-117247515-A Polyimide containing Trringer's Base element and gas separation membrane and method prepared by polyimide 西北工业大学 2023-12-19 CN claimed
CN-116854913-A Preparation method of high-impact-resistance bismaleimide resin 西北工业大学 2023-10-10 CN claimed
CN-116769161-A Polyimide with low CTE and high light transmittance, diamine monomer thereof and preparation method thereof 河北科技大学 2023-09-19 CN claimed
CN-110229158-B Thermosetting polyimide precursor with low melt viscosity and suitable for RTM (resin transfer molding) and preparation method thereof 西北工业大学 2022-06-07 CN claimed
CN-110218287-B High-performance self-repairing polyimide based on dynamic imine bond and preparation method thereof 西北工业大学 2022-03-15 CN claimed
US-20100009081-A1 3-{[4-(2-Chloro-4-nitrophenylazo)-phenyl]-ethyl-amino}-2-methyl-propionic acid vinyl ester; ink jet printing; dyeing and printing of synthetic textile material and fiber blends; dyeings on polyester with improved washfastness properties obtained if dyestuffs contain a vinyl ester group in coupling DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND (DE) 2010-01-14 US claimed
EP-2084232-A1 DISPERSE AZO DYESTUFFS DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2009-08-05 EP claimed
WO-2008055846-A1 DISPERSE AZO DYESTUFFS DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 2008-05-15 WO claimed
EP-1848713-A2 AMIDE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS F.HOFFMANN-LA ROCHE AG (CH) 2007-10-31 EP claimed
US-20060116407-A1 Amide derivatives HOFFMANN-LA ROCHE INC. 2006-06-01 US claimed
WO-2006053778-A2 AMIDE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS F. HOFFMANN-LA ROCHE AG (CH) 2006-05-26 WO claimed
US-6372030-B1 INK VEHICLE SELECTED FROM 4-(HEXADECYLAMINO)BENZYLAMINE, N-OCTANOYL-N-METHYL GLUCAMINE, OCTANOIC HYDRAZIDE, 4-HEXADECYL SULFONYL ANILINE, A CONDUCTIVE COMPLEX OF AN AMINE COMPOUND WITH A PHOSPHORUS OR SULFUR-CONTAINING ACID XEROX CORPORATION 2002-04-16 US claimed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US claimed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060116407-A1 Amide derivatives GLS, SDHA, GLS2 FFAR4 2074/4885PDE7A 3306/4885TDP1 4409/4885
US-20100009081-A1 3-{[4-(2-Chloro-4-nitrophenylazo)-phenyl]-ethyl-amino}-2-methyl-propionic acid vinyl ester; ink jet printing; dyeing and printing of synthetic textile material and fiber blends; dyeings on polyester with improved washfastness properties obtained if dyestuffs contain a vinyl ester group in coupling WDR77, PRMT7, CBR3 FFAR4 166/4885PDE7A 1396/4885TDP1 3394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.