Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2971206 | 1.00 | RET (0.32) | RETMAPK14CAMK1D | |
| SCHEMBL2976032 | 1.00 | RET (0.32) | RETMAPK14CAMK1D | |
| SCHEMBL2978135 | 1.00 | RET (0.32) | RETMAPK14CAMK1D | |
| SCHEMBL3980470 | 0.83 | TDP1 (0.32) | — | |
| SCHEMBL2971676 | 0.78 | — | — | |
| SCHEMBL2978032 | 0.78 | — | — | |
| SCHEMBL3990030 | 0.75 | LMNA (0.43) | — | |
| SCHEMBL15107725 | 0.70 | — | — | |
| SCHEMBL3980471 | 0.68 | SCN1A (0.32) | — | |
| SCHEMBL8615097 | 0.67 | GAA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487133-B2 | Substituted bicyclo [4.1.0] heptane-7-carboxylic acid amides and derivatives thereof as food flavor substances | SYMRISE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-8487133-B2 | Substituted bicyclo [4.1.0] heptane-7-carboxylic acid amides and derivatives thereof as food flavor substances | SYMRISE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-8487133-B2 | Substituted bicyclo [4.1.0] heptane-7-carboxylic acid amides and derivatives thereof as food flavor substances | SYMRISE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-20100189863-A1 | SUBSTITUTED BICYCLO [4.1.0] HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES | SYMRISE GMBH & CO.KG (DE) | 2010-07-29 | — | — | US | disclosed |
| EP-2079322-A1 | SUBSTITUTED BICYCLOÝ4.1.0¨HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES | Symrise GmbH & Co. KG (DE) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008046895-A1 | SUBSTITUTED BICYCLO[4.1.0]HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2008-04-24 | — | — | WO | disclosed |
| WO-2008046895-A1 | SUBSTITUTED BICYCLO[4.1.0]HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189863-A1 | SUBSTITUTED BICYCLO [4.1.0] HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES | HCAR3, TAS2R1, HCAR1 | RET 82/4885MAPK14 1430/4885CAMK1D 2639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.