Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.50 |
| ▸ | ERN1 | O75460 | 3/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CCNH | P51946 | 1/20 | 0.44 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311592 | 1.00 | PARP1 (0.50) | PARP1ERN1BAZ2BBAZ2ADHODH | |
| SCHEMBL31422694 | 0.83 | PARP1 (0.64) | PARP1ERN1DHODHCCNT1CCND1 | |
| SCHEMBL2431097 | 0.83 | PARP1 (0.64) | PARP1ERN1DHODHCCNT1CCND1 | |
| SCHEMBL8310029 | 0.82 | KMO (0.52) | — | |
| SCHEMBL4327798 | 0.82 | KMO (0.52) | — | |
| SCHEMBL6999225 | 0.81 | DHODH (0.63) | PARP1ERN1DHODHCSF1RFLT1 | |
| SCHEMBL29788172 | 0.77 | DHODH (0.70) | PARP1ERN1DHODHCSF1RFLT1 | |
| SCHEMBL43553 | 0.77 | DHODH (0.70) | PARP1ERN1DHODHCSF1RFLT1 | |
| SCHEMBL3717105 | 0.77 | MAPT (0.60) | PARP1ERN1BAZ2BBAZ2ADHODH | |
| SCHEMBL5605353 | 0.77 | PARP1 (0.78) | PARP1ERN1DHODHCSF1RFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138416-A1 | OXIME CARBAMOYL DERIVATIVES AS MODULATORS OF FATTY ACID AMIDES HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-19 | — | — | WO | disclosed |