SCHEMBL431177

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10134626	0.99	ALDH1A1 (0.94)	ALDH1A1HTTGAAKDM4ECYP1A2
	SCHEMBL19769221	0.98	ALDH1A1 (1.00)	ALDH1A1HTTGAAKDM4ECYP1A2
	SCHEMBL19769236	0.89	ALDH1A1 (0.77)	ALDH1A1HTTGAAKDM4ECYP1A2
	SCHEMBL430666	0.89	ALDH1A1 (1.00)	ALDH1A1HTTGAAKDM4ECYP1A2
	SCHEMBL19769240	0.80	ALDH1A1 (1.00)	ALDH1A1HTTGAAKDM4ECYP1A2
	SCHEMBL429207	0.79	ALDH1A1 (1.00)	ALDH1A1HTTGAAKDM4ECYP1A2
	SCHEMBL430534	0.78	MAPT (1.00)	ALDH1A1HTTGAAKDM4ENPSR1
	SCHEMBL13941637	0.77	ALDH1A1 (0.96)	ALDH1A1HTTGAAKDM4ECYP1A2
	SCHEMBL429326	0.76	MAPT (1.00)	ALDH1A1HTTGAAKDM4ECYP1A2
	SCHEMBL4111884	0.75	ALDH1A1 (0.75)	ALDH1A1HTTGAAKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.