Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.80 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.77 |
| ▸ | EEF2K | O00418 | 9/20 | 0.75 |
| ▸ | HPGD | P15428 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431177 | 0.98 | ALDH1A1 (0.96) | ALDH1A1HTTKDM4EGAACYP1A2 | |
| SCHEMBL10134626 | 0.97 | ALDH1A1 (0.94) | ALDH1A1HTTKDM4EGAACYP1A2 | |
| SCHEMBL19769236 | 0.87 | ALDH1A1 (0.77) | ALDH1A1HTTKDM4EGAACYP1A2 | |
| SCHEMBL430666 | 0.87 | ALDH1A1 (1.00) | ALDH1A1HTTKDM4EGAACYP1A2 | |
| SCHEMBL19769240 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HTTKDM4EGAACYP1A2 | |
| SCHEMBL13941637 | 0.79 | ALDH1A1 (0.96) | ALDH1A1HTTKDM4EGAACYP1A2 | |
| SCHEMBL429326 | 0.78 | MAPT (1.00) | ALDH1A1HTTKDM4EGAACYP1A2 | |
| SCHEMBL429207 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HTTKDM4EGAACYP1A2 | |
| SCHEMBL4111884 | 0.77 | ALDH1A1 (0.75) | ALDH1A1HTTKDM4EGAACYP1A2 | |
| SCHEMBL430534 | 0.76 | MAPT (1.00) | ALDH1A1HTTKDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180015077-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTION | NAKAMURA, ROBERT | 2018-01-18 | — | — | US | disclosed |
| US-20180015077-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTION | NAKAMURA, ROBERT | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015077-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTION | CD4, CCR5, MMP8 | ALDH1A1 482/4885HTT 3323/4885KDM4E 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.