Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.93 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.93 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.93 |
| ▸ | CA1 | P00915 | 10/20 | 0.76 |
| ▸ | CA2 | P00918 | 10/20 | 0.76 |
| ▸ | CA9 | Q16790 | 9/20 | 0.76 |
| ▸ | CA12 | O43570 | 6/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 3/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301505 | 0.88 | CA1 (0.80) | MEN1KMT2ACACNA1BAPBA1CA1 | |
| SCHEMBL9787783 | 0.83 | RAB9A (0.78) | MEN1KMT2ACACNA1BAPBA1NPC1 | |
| SCHEMBL15888499 | 0.83 | CA1 (0.86) | MEN1KMT2ACACNA1BAPBA1CA1 | |
| SCHEMBL4305965 | 0.82 | CA1 (0.89) | MEN1KMT2ACACNA1BAPBA1CA1 | |
| SCHEMBL13625624 | 0.81 | CA1 (0.72) | MEN1KMT2ACACNA1BAPBA1CA1 | |
| SCHEMBL13401865 | 0.81 | CA1 (0.86) | MEN1KMT2ACACNA1BAPBA1CA1 | |
| SCHEMBL30628487 | 0.81 | CA1 (0.86) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL6046379 | 0.80 | MEN1 (0.90) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL8868584 | 0.80 | CA2 (0.86) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL11807861 | 0.79 | MEN1 (0.87) | MEN1KMT2ACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140743-A2 | BLOOD IMAGING | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2009-11-26 | — | — | WO | disclosed |