SCHEMBL4312697

SCHEMBL4312697

CCCC(C(=O)O)c1ccc(F)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
HPGD P15428 2/20 0.46
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
SLC6A2 P23975 1/20 0.42
SLC6A3 Q01959 1/20 0.42
AKR1C3 P42330 2/20 0.41
AKR1C2 P52895 2/20 0.41
GAA P10253 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HTR7 P34969 1/20 0.41
MME P08473 1/20 0.40
HTT P42858 2/20 0.40
MAPT P10636 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KDM4E B2RXH2 1/20 0.40
FFAR1 O14842 1/20 0.40
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2489621 0.89 HTR7 (0.46) ALDH1A1HPGDPTGS1PTGS2HTR7
SCHEMBL29009923 0.88 LMNA (0.46) PTGS1PTGS2GAAHTR7MME
SCHEMBL19182879 0.85 AKR1C3 (0.53) PTGS1PTGS2AKR1C3AKR1C2
SCHEMBL2019275 0.85 AKR1C3 (0.53) PTGS1PTGS2AKR1C3AKR1C2
SCHEMBL27658097 0.84 ALDH1A1 (0.45) ALDH1A1HPGDSLC6A2SLC6A3HTR7
SCHEMBL7086595 0.84 ALDH1A1 (0.45) ALDH1A1HPGDSLC6A2SLC6A3HTR7
SCHEMBL7907443 0.83 PTGS1 (0.41) ALDH1A1PTGS1PTGS2GAAL3MBTL1
SCHEMBL7912554 0.83 PTGS1 (0.41) ALDH1A1PTGS1PTGS2GAAL3MBTL1
SCHEMBL633268 0.83 ESR1 (0.49) ALDH1A1PTGS1PTGS2SLC6A2SLC6A3
SCHEMBL7907447 0.83 PTGS1 (0.41) ALDH1A1PTGS1PTGS2GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1260265-C Polyhydroxy alkanoate and process for producing them with microbe CANON KK (JP) 2006-06-21 CN claimed
CN-1321695-A Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation CANON KK (JP) 2001-11-14 CN claimed
CN-103080080-B 6,7-dihydro-5H-benzo [7] takes turns ene derivative, its preparation method, the pharmaceutical preparation comprising it and its purposes for the preparation of medicine BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-08-26 CN disclosed
CN-103080080-A 6,7-dihydro-5h-benzo[7]annulene derivatives, process for preparation thereof, pharmaceutical preparations comprising them, and the use thereof for production of medicaments BAYER IP GMBH 2013-05-01 CN disclosed
CN-102292319-A Novel substituted octahydrocyclopenta(C)pyrrol-4-amines as calcium channel blockers 2011-12-21 CN disclosed
CN-1972938-B Cyclic amine compound TAISHO PHARMACEUTICAL CO LTD 2010-09-29 CN disclosed
WO-2009157019-A2 PROCESS FOR PREPARING EZETIMIBE USING NOVEL ALLYL INTERMEDIATES IND-SWIFT LABORATORIES LIMITED (IN) 2009-12-30 WO disclosed
CN-1972938-A Cyclic amine compound TAISHO PHARMACEUTICAL CO LTD (JP) 2007-05-30 CN disclosed
CN-1260266-C Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation CANON KK (JP) 2006-06-21 CN disclosed
CN-1321695-A Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation CANON KK (JP) 2001-11-14 CN disclosed