Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CCKAR | P32238 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627044 | 1.00 | POLB (0.52) | POLBSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL16454928 | 0.88 | SMN1; SMN2 (0.52) | POLBSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4452303 | 0.84 | HTR1A (0.60) | POLBSMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL13626256 | 0.84 | HTR1A (0.60) | POLBSMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL22738954 | 0.76 | MEN1 (0.52) | POLBSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4051880 | 0.75 | KMT2A (0.52) | POLBSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL23440313 | 0.75 | HPGD (0.71) | POLBSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL18397598 | 0.75 | HPGD (0.71) | POLBSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL29699833 | 0.75 | HPGD (0.71) | POLBSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL28504587 | 0.73 | HPGD (0.72) | POLBSMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138416-A1 | OXIME CARBAMOYL DERIVATIVES AS MODULATORS OF FATTY ACID AMIDES HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-19 | — | — | WO | claimed |
| WO-2009138416-A1 | OXIME CARBAMOYL DERIVATIVES AS MODULATORS OF FATTY ACID AMIDES HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-19 | — | — | WO | disclosed |