Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | CCKAR | P32238 | 1/20 | 0.60 |
| ▸ | HTR5A | P47898 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 4/20 | 0.44 |
| ▸ | BCR | P11274 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452303 | 1.00 | HTR1A (0.60) | HTR1AADORA3CCKARHTR5AABL1 | |
| SCHEMBL13627044 | 0.84 | POLB (0.52) | HTR1AADORA3CCKARHTR5APOLB | |
| SCHEMBL4313684 | 0.84 | POLB (0.52) | HTR1AADORA3CCKARHTR5APOLB | |
| SCHEMBL4049840 | 0.79 | HDAC3 (0.47) | HTR1AADORA3CCKARHTR5AABL1 | |
| SCHEMBL16454928 | 0.77 | SMN1; SMN2 (0.52) | POLBNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL4326042 | 0.75 | HDAC3 (0.43) | ABL1BCRHDAC3HDAC1HDAC2 | |
| SCHEMBL13626452 | 0.75 | HTR1A (1.00) | HTR1AADORA3CCKARHTR5APOLB | |
| SCHEMBL4318956 | 0.75 | HTR1A (1.00) | HTR1AADORA3CCKARHTR5APOLB | |
| SCHEMBL4323646 | 0.73 | NPSR1 (0.49) | HDAC1POLBNPC1ALDH1A1HPGD | |
| SCHEMBL4313679 | 0.71 | HTR1A (0.55) | HTR1AADORA3CCKARHTR5AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138416-A1 | OXIME CARBAMOYL DERIVATIVES AS MODULATORS OF FATTY ACID AMIDES HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-19 | — | — | WO | disclosed |