Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 1.00 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 1.00 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.72 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.72 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.72 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.72 |
| ▸ | PTGFR | P43088 | 3/20 | 0.72 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | PTGIR | P43119 | 2/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | PGR | P06401 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| [3H]Pgd2 SCHEMBL13260237 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL4315669 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL13399729 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL23352891 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| Prostaglandin D2 SCHEMBL2508829 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL24033138 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL2508831 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL22425683 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL22425684 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL29462111 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20150309021-A1 | Advanced Drug Development and Manufacturing | LOS ALAMOS NATIONAL SECURITY, LLC | 2015-10-29 | — | — | US | disclosed |
| EP-2511844-B1 | X-ray microscope | XRPRO SCIENCES INC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2511844-A2 | Advanced drug development and manufacturing | Los Alamos National Security, LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| EP-2084519-B1 | X-RAY FLUORESCENCE ANALYSIS METHOD | LOS ALAMOS NAT SECURITY LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2084519-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | Los Alamos National Security, LLC (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008127291-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-10-23 | — | — | WO | disclosed |