Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 1.00 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 1.00 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.72 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.72 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.72 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.72 |
| ▸ | PTGFR | P43088 | 3/20 | 0.72 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | PTGIR | P43119 | 2/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | PGR | P06401 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| [3H]Pgd2 SCHEMBL4315674 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL13260237 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL4315669 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL13399729 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| Prostaglandin D2 SCHEMBL2508829 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL24033138 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL2508831 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL22425683 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL22425684 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 | |
| [3H]Pgd2 SCHEMBL29462111 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916257-A | PGD 2 DPr2 and thromboxane A 2 Dual antagonists of the TPr receptor and their use for the treatment of adaptive immune responses or thrombotic conditions | 应用医疗技术有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-11583517-B2 | Dual antagonist of PGD2/DPr2 and Thromboxane A2/TPr receptors and use for treatment of maladaptive immune response or thrombotic diathesis | APPLIED MEDICAL TECHNOLOGIES LLC (US) | 2023-02-21 | — | — | US | disclosed |
| EP-4126050-A1 | DUAL ANTAGONIST OF PGD2/DPR2 AND THROMBOXANE A2/TPR RECEPTORS AND USE FOR TREATMENT OF MALAPTIVE IMMUNE RESPONSE OR THROMBOTIC DIATHESIS | Applied Medical Technologies LLC (US) | 2023-02-08 | — | — | EP | disclosed |
| US-20220184031-A1 | DUAL ANTAGONIST OF PGD2/DPR2 AND THROMBOXANE A2/TPR RECEPTORS AND USE FOR TREATMENT OF MALADAPTIVE IMMUNE RESPONSE OR THROMBOTIC DIATHESIS | APPLIED MEDICAL TECHNOLOGIES LLC (US) | 2022-06-16 | — | — | US | disclosed |
| US-20210139435-A1 | PROSTAGLANDIN ANALOGS AND USES THEREOF | Lifex Biolabs, Inc. | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139435-A1 | PROSTAGLANDIN ANALOGS AND USES THEREOF | PTGDR, NR3C1, PTGIR | ALDH1A1 1158/4885PTGDR2 4/4885SLCO2A1 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.