[3H]Pgd2

[3H]Pgd2

SCHEMBL13399729

CCCCC[C@H](O)/C=C/[C@H]1C(=O)C[C@H](O)C1C/C=C\CCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
PTGDR2 Q9Y5Y4 3/20 1.00
SLCO2A1 Q92959 2/20 1.00
PTGER4 P35408 5/20 0.72
PTGER2 P43116 4/20 0.72
PTGER1 P34995 4/20 0.72
PTGER3 P43115 4/20 0.72
PTGFR P43088 3/20 0.72
TBXA2R P21731 3/20 0.72
HPGD P15428 3/20 0.72
PTGIR P43119 2/20 0.72
NR1I2 O75469 1/20 0.72
ESR1 P03372 1/20 0.72
PGR P06401 1/20 0.72
TSHR P16473 1/20 0.72
MAPK1 P28482 1/20 0.72
OPRK1 P41145 1/20 0.72
PDE4D Q08499 1/20 0.72
LMNA P02545 3/20 0.67
PTGDR Q13258 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
[3H]Pgd2 SCHEMBL4315674 1.00 ALDH1A1 (1.00) ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2
[3H]Pgd2 SCHEMBL13260237 1.00 ALDH1A1 (1.00) ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2
[3H]Pgd2 SCHEMBL4315669 1.00 ALDH1A1 (1.00) ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2
[3H]Pgd2 SCHEMBL23352891 1.00 ALDH1A1 (1.00) ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2
Prostaglandin D2 SCHEMBL2508829 1.00 ALDH1A1 (1.00) ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2
[3H]Pgd2 SCHEMBL24033138 1.00 ALDH1A1 (1.00) ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2
[3H]Pgd2 SCHEMBL2508831 1.00 ALDH1A1 (1.00) ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2
[3H]Pgd2 SCHEMBL22425683 1.00 ALDH1A1 (1.00) ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2
[3H]Pgd2 SCHEMBL22425684 1.00 ALDH1A1 (1.00) ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2
[3H]Pgd2 SCHEMBL29462111 1.00 ALDH1A1 (1.00) ALDH1A1PTGDR2SLCO2A1PTGER4PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174476-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF PROSTAGLANDINS AND RELATED COMPOUNDS TECHFIELDS PHARMA CO., LTD. (CN) 2023-06-08 US disclosed
US-8722739-B2 Amino acid salts of prostaglandins NOVAER HOLDINGS, INC. (US) 2014-05-13 US disclosed
US-20100105771-A1 AMINO ACID SALTS OF PROSTAGLANDINS NOVAER HOLDINGS, INC. 2010-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174476-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF PROSTAGLANDINS AND RELATED COMPOUNDS HPGDS, PTGER1, PTGIS ALDH1A1 1878/4885PTGDR2 17/4885SLCO2A1 130/4885
US-20100105771-A1 AMINO ACID SALTS OF PROSTAGLANDINS PTGIS, PTGES, PTGIR ALDH1A1 3538/4885PTGDR2 10/4885SLCO2A1 1547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.