SCHEMBL4315892

SCHEMBL4315892

O=C(O)C1(C2CCCCC2)C2OC2C2OC2C1(C(=O)O)C1CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.34
HTT P42858 1/20 0.34
MAPK1 P28482 2/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33
CYP2C19 P33261 1/20 0.33
THPO P40225 1/20 0.33
STAT6 P42226 1/20 0.33
HIF1A Q16665 1/20 0.33
NPC1 O15118 1/20 0.33
GMNN O75496 1/20 0.33
MTOR P42345 1/20 0.33
RAB9A P51151 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10897858 0.77
SCHEMBL8852584 0.65 LMNA (0.33) LMNAMAPK1TP53NFKB1CYP2C19
SCHEMBL3839479 0.64 CYP3A4 (0.38) LMNAMAPK1CYP2C19THPONPC1
SCHEMBL21133752 0.64 CES2 (0.36) LMNANPC1RAB9ASMN1; SMN2TSHR
SCHEMBL210214 0.64 CES2 (0.36) LMNACYP2C19THPONPC1RAB9A
SCHEMBL10534819 0.64 LMNA (0.32) LMNAMAPK1TP53NFKB1CYP2C19
SCHEMBL7876266 0.62 CYP3A4 (0.44) LMNAMAPK1CYP2C19THPONPC1
SCHEMBL10938537 0.62 CYP3A4 (0.44) LMNAMAPK1CYP2C19THPONPC1
SCHEMBL2530342 0.62 CYP3A4 (0.44) LMNAMAPK1CYP2C19THPONPC1
SCHEMBL1052271 0.62 CYP3A4 (0.40) LMNAMAPK1CYP2C19THPONPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240230568-A1 EMBEDDED SENSOR SYSTEM FOR MEASUREMENT AND MONITORING OF THE PORE SOLUTION ELECTRICAL RESISTIVITY IN CONCRETE MATERIALS AND STRUCTURES PENN STATE RES FOUND (US) 2024-07-11 US disclosed
US-7524388-B2 contacting a liquid crystalline polymer fibrous web such as polyethylene terephthlate having interfiber spaces, cowound with a carrier( polytetrafluoroethylene) in vacuum with curable epoxy resin to provide an infiltrated, co-wound liquid crystalline polymer fibrous web, removing vacuum, pressurizing WORLD PROPERTIES, INC. (US) 2009-04-28 US disclosed
WO-2007076014-A2 THERMAL MANAGEMENT CIRCUIT MATERIALS, METHOD OF MANUFACTURE THEREOF, AND ARTICLES FORMED THEREFROM WORLD PROPERTIES, INC. (US) 2007-07-05 WO disclosed
US-20070148467-A1 THERMAL MANAGEMENT CIRCUIT MATERIALS, METHOD OF MANUFACTURE THEREOF, AND ARTICLES FORMED THEREFROM WORLD PROPERTIES, INC. (US) 2007-06-28 US disclosed
US-20060258241-A1 Composites, Method of Manufacture Thereof, And Articles Formed Therefrom WORLD PROPERTIES, INC. (US) 2006-11-16 US disclosed
US-4292214-A LIGNIN-CELLULOSE EPOXY RESIN, POLYISOCYANATE BLOUNT DAVID H 1981-09-29 US disclosed
US-3960813-A ADNC BLENDSADIPODI(NITRILE CARBONATE) ATLANTIC RICHFIELD COMPANY (US) 1976-06-01 US disclosed