Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22640750 | 0.74 | CES2 (0.39) | CES2CES1KDM4EEPHX1NPC1 | |
| SCHEMBL210214 | 0.70 | CES2 (0.36) | CES2CES1KDM4EEPHX1NPC1 | |
| SCHEMBL3839479 | 0.70 | CYP3A4 (0.38) | CES2CES1KDM4EEPHX1NPC1 | |
| SCHEMBL2747723 | 0.69 | HSD11B1 (0.42) | HSD11B1TSHR | |
| SCHEMBL2530342 | 0.68 | CYP3A4 (0.44) | CES2CES1KDM4EEPHX1NPC1 | |
| SCHEMBL7876266 | 0.68 | CYP3A4 (0.44) | CES2CES1KDM4EEPHX1NPC1 | |
| SCHEMBL10938537 | 0.68 | CYP3A4 (0.44) | CES2CES1KDM4EEPHX1NPC1 | |
| SCHEMBL50170 | 0.68 | CYP3A4 (0.44) | CES2CES1KDM4EEPHX1NPC1 | |
| SCHEMBL1052271 | 0.68 | CYP3A4 (0.40) | CES2CES1KDM4EEPHX1NPC1 | |
| SCHEMBL8796429 | 0.68 | CYP3A4 (0.44) | CES2CES1KDM4EEPHX1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10343972-B2 | Fullerene derivative, fluororesin composition, and lubricant | SHOWA DENKO K.K. (JP) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10343972-B2 | Fullerene derivative, fluororesin composition, and lubricant | PFN1, FSCN1, FLNA | CES2 2207/4885CES1 3994/4885KDM4E 4174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.