Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | XIAP | P98170 | 1/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.57 |
| ▸ | CPA1 | P15085 | 6/20 | 0.53 |
| ▸ | CPA3 | P15088 | 3/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | CPB1 | P15086 | 1/20 | 0.53 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.53 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490844 | 1.00 | CYP1A2 (0.61) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL4826192 | 1.00 | CYP1A2 (0.61) | CYP1A2ALPIPKMPTGS1XIAP | |
| Bromide SCHEMBL1596942 | 0.98 | CYP1A2 (0.59) | CYP1A2ALPIPKMPTGS1XIAP | |
| Ethylenediamine SCHEMBL5766632 | 0.92 | ALPI (0.55) | CYP1A2ALPIPKMPTGS1XIAP | |
| Toluene SCHEMBL6466953 | 0.90 | CYP1A2 (0.52) | CYP1A2ALPIPKMPTGS1XIAP | |
| Toluene SCHEMBL6466957 | 0.90 | CYP1A2 (0.52) | CYP1A2ALPIPKMPTGS1XIAP | |
| Acetonitrile SCHEMBL27829383 | 0.89 | CYP1A2 (0.50) | CYP1A2ALPIPKMPTGS1XIAP | |
| Nitrous Acid SCHEMBL9333501 | 0.89 | CYP1A2 (0.50) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL6382096 | 0.88 | SRR (0.57) | PTGS1CPA1SRR | |
| SCHEMBL5766696 | 0.87 | CYP1A2 (0.48) | CYP1A2ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388098-B2 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | claimed |
| EP-1487836-B1 | ETHANE-1,2-DIAMINO-BIS (2R)-2-BROMO-3-PHENYLPROPANOATE|, METHOD FOR PRODUCTION AND USE THEREOF | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-09-06 | — | — | EP | claimed |
| US-7009047-B2 | Ethane-1,2-diaminium bis[(2R)-2-bromo-3-phenylpropanoate], processes for its preparation and its use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-03-07 | — | — | US | claimed |
| CN-1639109-A | Kinetic resolution of isomers and resolved isomers | BRISTOL MYERS SQUIBB CO (US) | 2005-07-13 | — | — | CN | claimed |
| EP-1056707-B1 | PROCESS FOR PREPARING (R)-2-BROMO-3-PHENYL-PROPIONIC ACID | ZAMBON SPA (IT) | 2004-12-22 | — | — | EP | claimed |
| EP-1487836-A1 | ETHANE-1,2-DIAMINO-BIS (2R)-2-BROMO-3-PHENYLPROPANOATE], METHOD FOR PRODUCTION AND USE THEREOF | Aventis Pharma Deutschland GmbH (DE) | 2004-12-22 | — | — | EP | claimed |
| EP-1138671-B1 | Production method of aromatic acylthiocarboxylic acid derivative | AJINOMOTO KK (JP) | 2004-09-01 | — | — | EP | claimed |
| US-20040010039-A1 | Ethane-1,2-diaminium bis[(2R)-2-bromo-3-phenylpropanoate], processes for its preparation and its use | DEUTSCHE BANK AG NEW YORK BRANCH | 2004-01-15 | — | — | US | claimed |
| WO-2003078434-A1 | ETHANE-1,2-DIAMINO-BIS[(2R)-2-BROMO-3-PHENYLPROPANOATE], METHOD FOR PRODUCTION AND USE THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-09-25 | — | — | WO | claimed |
| EP-1324975-A2 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | Bristol-Myers Squibb Company (US) | 2003-07-09 | — | — | EP | claimed |
| US-20020010358-A1 | Production method of aromatic carboxylic acid derivative | AJINOMOTO CO., INC. (JP) | 2002-01-24 | — | — | US | claimed |
| EP-1138671-A1 | Production method of aromatic acylthiocarboxylic acid derivative | Ajinomoto Co., Inc. (JP) | 2001-10-04 | — | — | EP | claimed |
| WO-2001058837-A2 | PROCESS FOR THE PREPARATION OF (R)-2-BROMO-3-PHENYL-PROPIONIC ACID | DSM N.V. (NL) | 2001-08-16 | — | — | WO | claimed |
| WO-2001058865-A1 | METHOD FOR THE PREPARATION OF (S)-2-ACETYLTHIO-3-PHENYLPROPIONIC ACID | DSM N.V. (NL) | 2001-08-16 | — | — | WO | claimed |
| EP-1056707-A1 | PROCESS FOR PREPARING (R)-2-BROMO-3-PHENYL-PROPIONIC ACID | ZAMBON GROUP S.p.A. (IT) | 2000-12-06 | — | — | EP | claimed |
| EP-1056715-A1 | PROCESS FOR PREPARING 2-ACETYLTHIO-3-PHENYL-PROPIONIC ACID AND THE SALTS THEREOF | ZAMBON GROUP S.p.A. (IT) | 2000-12-06 | — | — | EP | claimed |
| US-6103931-A | Process for preparing (R)-2-bromo-3-phenyl-propionic acid | ZAMBON GROUP S.P.A. (IT) | 2000-08-15 | — | — | US | claimed |
| US-6080881-A | Process for preparing 2-acetythio-3-phenyl-propionic acid and the salts thereof | ZAMBON GROUP S.P.A. (IT) | 2000-06-27 | — | — | US | claimed |
| WO-1999042438-A1 | PROCESS FOR PREPARING 2-ACETYLTHIO-3-PHENYL-PROPIONIC ACID AND THE SALTS THEREOF | ZAMBON GROUP S.P.A. (IT) | 1999-08-26 | — | — | WO | claimed |
| WO-1999042431-A1 | PROCESS FOR PREPARING (R)-2-BROMO-3-PHENYL-PROPIONIC ACID | ZAMBON GROUP S.P.A. (IT) | 1999-08-26 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010358-A1 | Production method of aromatic carboxylic acid derivative | AADAC, DDC, AADAT | CYP1A2 299/4885ALPI 2302/4885PKM 3743/4885 |
| US-20040010039-A1 | Ethane-1,2-diaminium bis[(2R)-2-bromo-3-phenylpropanoate], processes for its preparation and its use | ACE, ECE1, ECE2 | CYP1A2 427/4885ALPI 2674/4885PKM 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.