Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | NNMT | P40261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4317630 | 1.00 | L3MBTL1 (0.48) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL27761171 | 0.84 | KMT2A (0.46) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8307069 | 0.79 | NNMT (0.46) | L3MBTL1SMN1; SMN2MEN1KMT2ANNMT | |
| SCHEMBL8307070 | 0.79 | NNMT (0.46) | L3MBTL1SMN1; SMN2MEN1KMT2ANNMT | |
| SCHEMBL4451421 | 0.77 | L3MBTL1 (0.71) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19733323 | 0.77 | L3MBTL1 (0.71) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL14277946 | 0.77 | ESR1 (0.46) | RAB9ASMN1; SMN2MEN1KMT2APABPC1 | |
| Water SCHEMBL4316877 | 0.76 | NPC1 (0.74) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL23182807 | 0.75 | KMT2A (0.57) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4317117 | 0.74 | RAB9A (0.58) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061748-A2 | CATALYTIC ASYMMETRIC SYNTHESIS OF PRIMARY AMINES VIA BORANE REDUCTION OF OXIME ETHERS USING SPIROBORATE ESTERS | Office Of Intellectual Property And Technology (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008027740-A2 | CATALYTIC ASYMMETRIC SYNTHESIS OF PRIMARY AMINES VIA BORANE REDUCTION OF OXIME ETHERS USING SPIROBORATE ESTERS | OFFICE OF INTELLECTUAL PROPERTY AND TECHNOLOGY (US) | 2008-03-06 | — | — | WO | disclosed |