Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311625 | 0.84 | FYN (0.47) | HRH1DRD2HTR2ACDK2BRAF | |
| SCHEMBL3361078 | 0.83 | CDK2 (0.54) | TAAR1HRH1DRD2HTR2ACDK2 | |
| SCHEMBL4317292 | 0.80 | BRAF (0.47) | TAAR1GPR84CNR1BRAF | |
| SCHEMBL4314900 | 0.80 | CSNK2A2 (0.48) | CNR1BRAFCSF1RPTGDR | |
| SCHEMBL4323633 | 0.78 | CYP4F2 (0.53) | HRH1BRAFCSF1R | |
| SCHEMBL5206069 | 0.76 | HRH1 (0.55) | TAAR1HRH1DRD2HTR2ACNR1 | |
| SCHEMBL3361755 | 0.74 | DRD2 (0.56) | TAAR1GPR84HRH1DRD2HTR2A | |
| SCHEMBL6659258 | 0.74 | HRH1 (0.50) | HRH1DRD2HTR2ACDK2CSF1R | |
| SCHEMBL6472975 | 0.71 | CYP1A2 (0.55) | TAAR1GPR84 | |
| SCHEMBL6283187 | 0.71 | MAP4K4 (0.48) | CDK2HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099774-A1 | INHIBITORS OF KINASE ACTIVITY | Cytopia Research Pty Ltd (AU) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008058341-A1 | INHIBITORS OF KINASE ACTIVITY | CYTOPIA RESEARCH PTY LTD (AU) | 2008-05-22 | — | — | WO | disclosed |