Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 3/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314900 | 0.88 | CSNK2A2 (0.48) | BRAFL3MBTL1CNR2CSF1RMEN1 | |
| SCHEMBL4317671 | 0.81 | CSF1R (0.53) | BRAFCSF1RHRH1RETPDGFRB | |
| SCHEMBL4323640 | 0.79 | CSF1R (0.66) | BRAFCSF1RMEN1KMT2ARET | |
| SCHEMBL4317692 | 0.78 | TAAR1 (0.48) | BRAFCSF1RHRH1 | |
| SCHEMBL4311625 | 0.78 | FYN (0.47) | BRAFSMN1; SMN2HRH1 | |
| SCHEMBL4324513 | 0.77 | CSF1R (0.66) | BRAFCSF1RRETPDGFRBKIT | |
| SCHEMBL3361078 | 0.77 | CDK2 (0.54) | BRAFL3MBTL1SMN1; SMN2HRH1 | |
| SCHEMBL14103993 | 0.76 | CYP4F2 (0.69) | CYP4F2CYP4A11LOXL2SLC7A5KDM5B | |
| SCHEMBL27167178 | 0.75 | CSF1R (0.67) | BRAFCSF1RMEN1GAAKMT2A | |
| SCHEMBL3475791 | 0.75 | CSF1R (0.68) | L3MBTL1CSF1RRETPDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099774-A1 | INHIBITORS OF KINASE ACTIVITY | Cytopia Research Pty Ltd (AU) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008058341-A1 | INHIBITORS OF KINASE ACTIVITY | CYTOPIA RESEARCH PTY LTD (AU) | 2008-05-22 | — | — | WO | disclosed |