Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24495860 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EKMT2AHPGD | |
| SCHEMBL22903989 | 0.77 | GAA (0.42) | ALDH1A1MAPTKDM4EKMT2AHPGD | |
| SCHEMBL4862778 | 0.77 | RECQL (0.48) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| SCHEMBL79874 | 0.73 | MAPK1 (0.37) | ALDH1A1HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL28722168 | 0.72 | GAA (0.47) | ALDH1A1MAPTKDM4EKMT2AHPGD | |
| SCHEMBL7963728 | 0.71 | GAA (0.51) | ALDH1A1MAPTKDM4EKMT2AHPGD | |
| SCHEMBL24488080 | 0.70 | GAA (0.38) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| SCHEMBL12324775 | 0.70 | CHRM2 (0.46) | MAPTHTTSMN1; SMN2CYP3A4 | |
| SCHEMBL29738271 | 0.70 | MAPK1 (0.40) | ALDH1A1KMT2ANPSR1CASP3 | |
| SCHEMBL15888456 | 0.69 | MAPK1 (0.37) | ALDH1A1HTTSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286060-A1 | Degradable polymer article | CIBA CORP. | 2009-11-19 | — | — | US | disclosed |
| US-20090286060-A1 | Degradable polymer article | CIBA CORP. | 2009-11-19 | — | — | US | disclosed |
| WO-2009135813-A1 | DEGRADABLE MATERIAL | BASF SE (DE) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009095344-A1 | DEGRADABLE MATERIAL | BASF SE (DE) | 2009-08-06 | — | — | WO | disclosed |
| EP-1922359-A1 | A DEGRADABLE POLYMER ARTICLE | Ciba Holding Inc. (CH) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007028731-A1 | A DEGRADABLE POLYMER ARTICLE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-03-15 | — | — | WO | disclosed |