Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL9901947 | 0.93 | ALDH1A1 (0.35) | MAPK1ALDH1A1ALOX15SMYD2ESR1 | |
| SCHEMBL16174761 | 0.89 | SMYD2 (0.33) | MAPK1SMYD2ESR1ESR2NR1H2 | |
| SCHEMBL7597173 | 0.88 | MGAM (0.35) | MAPK1ALDH1A1ALOX15SMYD2ESR1 | |
| SCHEMBL15888456 | 0.85 | MAPK1 (0.37) | MAPK1ALDH1A1ALOX15SMYD2ESR1 | |
| SCHEMBL704188 | 0.83 | MAPK1 (0.36) | MAPK1ALDH1A1ALOX15SMYD2ESR1 | |
| SCHEMBL707572 | 0.81 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15SMYD2ESR1 | |
| SCHEMBL31318429 | 0.81 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15SMYD2ESR1 | |
| SCHEMBL19720997 | 0.81 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15SMYD2ESR1 | |
| SCHEMBL18924906 | 0.81 | ALDH1A1 (0.41) | MAPK1ALDH1A1ALOX15SMYD2ESR1 | |
| SCHEMBL707090 | 0.81 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15SMYD2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2440 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12623993-B2 | Synthesis of vinyl cyclobutyl intermediates | AMGEN INC. (US) | 2026-05-12 | — | — | US | claimed |
| EP-4643858-A1 | METHODS AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF UTERINE DISEASE | Institut National de la Santé et de la Recherche Médicale (FR) | 2025-11-05 | — | — | EP | claimed |
| US-12441741-B2 | Ring closing synthesis of macrocyclic MCL-1 inhibitor intermediates | AMGEN INC. (US) | 2025-10-14 | — | — | US | claimed |
| US-12435049-B2 | Synthesis of vinylic protected alcohol intermediates | AMGEN INC. (US) | 2025-10-07 | — | — | US | claimed |
| CN-115745884-B | Opioid derivatives, intermediates and process for preparing the same | 绍兴赜军生物医药科技有限公司 | 2025-06-13 | — | — | CN | claimed |
| EP-4146636-B1 | SYNTHESIS OF VINYLIC PROTECTED ALCOHOL INTERMEDIATES | AMGEN INC (US) | 2025-06-11 | — | — | EP | claimed |
| US-20250154177-A1 | PYRROLOBENZODIAZEPINE INTERMEDIATES AND USES THEREOF | SIGMA-ALDRICH CO. LLC | 2025-05-15 | — | — | US | claimed |
| US-12247239-B2 | Chemo-enzymatic process for the preparation of homopropargylic alcohol | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2025-03-11 | — | — | US | claimed |
| CN-119562955-A | Pyrrolo-benzodiazepines intermediate and use thereof | 西格马-奥尔德里奇有限责任公司 | 2025-03-04 | — | — | CN | claimed |
| CN-118908912-A | Synthesis of vinyl protected alcohol intermediates | 安进公司 | 2024-11-08 | — | — | CN | claimed |
| WO-2006122020-A2 | PROCESS FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2006-11-16 | — | — | WO | claimed |
| WO-2006122216-A2 | PROCESSES FOR PRODUCTION OF PHENOLIC 4-BIPHENYLYLAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2006-11-16 | — | — | WO | claimed |
| CN-1756759-A | Process for preparing C-aryl glucoside SGLT2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2006-04-05 | — | — | CN | claimed |
| EP-1581543-A2 | METHODS OF PRODUCING C-ARYL GLUCOSIDE SGLT2 INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-10-05 | — | — | EP | claimed |
| US-20050124687-A1 | Process for synthesizing d-tocotrienols | COULADOUROS ELIAS A (GR) | 2005-06-09 | — | — | US | claimed |
| WO-2005035490-A2 | PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS | YASOO HEALTH, INC. (US) | 2005-04-21 | — | — | WO | claimed |
| WO-2004063209-A2 | METHODS OF PRODUCING C-ARYL GLUCOSIDE SGLT2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-07-29 | — | — | WO | claimed |
| US-20040138439-A1 | inhibitors of sodium dependent glucose transporters found in the intestine and kidney (SGLT2), and more particularly to a process of producing such compounds, for example 1-C-(substituted diphenylmethane-3-yl)- beta -D-glucopyranose | ASTRAZENECA AB (SE) | 2004-07-15 | — | — | US | claimed |
| US-6344537-B1 | RUBBER COMPOSITION WITH TWO THIIRANES AND PROTECTED GROUP WITH CARBONYL | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2002-02-05 | — | — | US | claimed |
| US-5250703-A | Glycosidase inhibitors; reducing azido lactone, decyclizing, protective silation, hydrolysis, epoxidation, hydrogenation, deprotecting | MONSANTO COMPANY (US) | 1993-10-05 | — | — | US | claimed |