Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.50 |
| ▸ | GLRB | P48167 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25760144 | 0.86 | GABRA1 (0.44) | GLRA3GLRBGABRA1GABRB1GAA | |
| SCHEMBL20099506 | 0.85 | GABRA1 (0.42) | GLRA3GLRBGABRA1GABRB1GAA | |
| SCHEMBL10551872 | 0.84 | LMNA (0.45) | GLRA3GLRBGAALMNARECQL | |
| SCHEMBL4319072 | 0.83 | GABRA1 (0.63) | GABRA1GABRB1THRATHRBGAA | |
| SCHEMBL227202 | 0.83 | GLRA3 (0.63) | GLRA3GLRBGAALMNARECQL | |
| SCHEMBL8659247 | 0.81 | GLRA3 (0.61) | GLRA3GLRBGAALMNARECQL | |
| SCHEMBL9355788 | 0.81 | GLRA3 (0.61) | GLRA3GLRBGAALMNARECQL | |
| SCHEMBL7629603 | 0.81 | GLRA3 (0.61) | GLRA3GLRBGAALMNARECQL | |
| Hydrochloric Acid SCHEMBL1943524 | 0.81 | GLRA3 (0.61) | GLRA3GLRBGAALMNARECQL | |
| SCHEMBL25760420 | 0.81 | LMNA (0.42) | GLRA3GLRBGABRA1GABRB1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847303-A | UNSATURATED KETONES | THE PROCTER & GAMBLE COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| US-4255304-A | DISCOLORATION INHIBITION | AMERICAN CYANAMID COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| US-4248594-A | PRINTING, DYEING NICKEL SALTS OF 4-HYDROXYBENZOIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1981-02-03 | — | — | US | disclosed |
| US-4144029-A | PREPARED BY REACTION OF A NICKEL P-HYDROXYBENZOATE WITH AN ORGANIC PHOSPHITE | AMERICAN CYANAMID COMPANY (US) | 1979-03-13 | — | — | US | disclosed |