Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783793 | 0.78 | TRPV1 (0.52) | TRPV1HSD11B1HCRTR1HCRTR2GAA | |
| SCHEMBL4776367 | 0.77 | TRPV1 (0.43) | TRPV1HSD11B1HCRTR1HCRTR2GAA | |
| SCHEMBL4319338 | 0.77 | TRPV1 (0.48) | TRPV1HSD11B1HCRTR1HCRTR2GAA | |
| SCHEMBL4327376 | 0.76 | TRPV1 (0.73) | TRPV1 | |
| SCHEMBL4327380 | 0.76 | TRPV1 (0.73) | TRPV1 | |
| SCHEMBL4320157 | 0.73 | EPHX2 (0.56) | TRPV1HSD11B1GAA | |
| SCHEMBL14973800 | 0.70 | EPHX2 (0.59) | TRPV1HSD11B1HCRTR1HCRTR2GAA | |
| SCHEMBL4482959 | 0.70 | EPHX2 (0.59) | TRPV1HSD11B1GAA | |
| SCHEMBL6988200 | 0.67 | HSD11B1 (0.70) | TRPV1HSD11B1GAA | |
| SCHEMBL26087182 | 0.67 | TRPV1 (0.67) | TRPV1HSD11B1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |