Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749459 | 0.98 | MAPK1 (0.50) | MAPK1MEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL1749829 | 0.81 | MAPK1 (0.49) | MAPK1MEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL1750708 | 0.79 | MAPK1 (0.47) | MAPK1MEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL12529289 | 0.79 | MAPK1 (0.47) | MAPK1MEN1KMT2AHDAC6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3433344 | 0.79 | MAPK1 (0.50) | MAPK1MEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL20379181 | 0.77 | MAPK1 (0.61) | MAPK1MEN1KMT2AHDAC6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30688337 | 0.76 | MAPK1 (0.59) | MAPK1MEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL1752743 | 0.75 | ALDH1A1 (0.45) | MAPK1MEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL13824130 | 0.75 | ALDH1A1 (0.44) | MAPK1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1750234 | 0.75 | MAPT (0.45) | MAPK1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090136570-A1 | Taste-Masked Tablets and Granules | UNIVERSITAT ZURICH (CH) | 2009-05-28 | — | — | US | claimed |
| US-20090136570-A1 | Taste-Masked Tablets and Granules | UNIVERSITAT ZURICH (CH) | 2009-05-28 | — | — | US | disclosed |
| WO-2007087188-A2 | TASTE-MASKED TABLETS AND GRANULES | MERCK & CO., INC. (US) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136570-A1 | Taste-Masked Tablets and Granules | TAS2R30, TAS2R40, TAS2R42 | MAPK1 2705/4885MEN1 4028/4885KMT2A 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.