Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235296 | 0.90 | ALOX5AP (0.78) | ALOX5APALOX5 | |
| SCHEMBL4317905 | 0.89 | ALOX5AP (0.80) | ALOX5APALOX5 | |
| SCHEMBL4324949 | 0.89 | ALOX5AP (0.76) | ALOX5APALOX5 | |
| SCHEMBL4331378 | 0.88 | ALOX5AP (0.60) | ALOX5APALOX5 | |
| SCHEMBL4312338 | 0.88 | ALOX5AP (0.69) | ALOX5APALOX5 | |
| SCHEMBL4328681 | 0.88 | ALOX5AP (0.57) | ALOX5APALOX5 | |
| SCHEMBL4312610 | 0.87 | ALOX5AP (0.56) | ALOX5APALOX5 | |
| SCHEMBL4318432 | 0.86 | ALOX5AP (0.64) | ALOX5APALOX5 | |
| SCHEMBL4321968 | 0.86 | ALOX5AP (0.66) | ALOX5AP | |
| SCHEMBL4318427 | 0.86 | ALOX5AP (0.62) | ALOX5APALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197883-A1 | Diphenyl Substituted Cycloalkanes, Compositions Containing Such Compounds and Methods Of Use | MERCK SHARP & DOHME CORP. | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197883-A1 | Diphenyl Substituted Cycloalkanes, Compositions Containing Such Compounds and Methods Of Use | ALOX5, LTC4S, ALOX15B | ALOX5AP 16/4885ALOX5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.