Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4470164 | 0.83 | SLC6A2 (0.53) | SLC6A3SLC6A2SLC6A4OPRM1OPRK1 | |
| SCHEMBL4467010 | 0.81 | GRIN2D (0.46) | SLC6A3SLC6A4DRD1 | |
| SCHEMBL4032877 | 0.72 | SLC6A2 (0.78) | SLC6A3SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL4321716 | 0.72 | SLC6A2 (0.54) | SLC6A3SLC6A2SLC6A4HSD17B2CYP2D6 | |
| SCHEMBL19010138 | 0.72 | SLC6A2 (0.56) | SLC6A3SLC6A2SLC6A4OPRM1OPRK1 | |
| SCHEMBL19010135 | 0.72 | SLC6A2 (0.56) | SLC6A3SLC6A2SLC6A4OPRM1OPRK1 | |
| SCHEMBL15131035 | 0.72 | SLC6A2 (0.56) | SLC6A3SLC6A2SLC6A4OPRM1OPRK1 | |
| SCHEMBL4328470 | 0.72 | SLC6A2 (0.49) | SLC6A3SLC6A2SLC6A4OPRM1OPRK1 | |
| SCHEMBL4319928 | 0.69 | SLC6A2 (0.46) | SLC6A3SLC6A2SLC6A4OPRM1OPRK1 | |
| SCHEMBL6998367 | 0.66 | SLC6A3 (1.00) | SLC6A3SLC6A2SLC6A4OPRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |