Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760912 | 0.75 | PKM (0.32) | PKM | |
| SCHEMBL424435 | 0.74 | PKM (0.42) | PKM | |
| SCHEMBL18171377 | 0.71 | — | — | |
| SCHEMBL4333948 | 0.70 | PKM (0.36) | PKM | |
| SCHEMBL23096814 | 0.67 | PKM (0.37) | PKM | |
| SCHEMBL16181727 | 0.67 | PKM (0.37) | PKM | |
| SCHEMBL11365017 | 0.67 | PKM (0.33) | PKM | |
| SCHEMBL21789023 | 0.66 | — | — | |
| SCHEMBL3843526 | 0.65 | PKM (0.36) | PKM | |
| SCHEMBL986904 | 0.62 | PKM (0.33) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511177-B2 | Fluoroadamantane derivative | ASAHI GLASS COMPANY, LIMITED (JP) | 2009-03-31 | — | — | US | disclosed |
| US-7488847-B2 | Fluorinated adamantane and its derivatives | ASAHI GLASS COMPANY, LIMITED (JP) | 2009-02-10 | — | — | US | disclosed |
| US-7402714-B2 | Fluoroadamantane derivative | ASAHI GLASS COMPANY, LIMITED (JP) | 2008-07-22 | — | — | US | disclosed |
| US-20080132736-A1 | FLUOROADAMANTANE DERIVATIVE | ASAHI GLASS COMPANY, LIMITED (JP) | 2008-06-05 | — | — | US | disclosed |
| US-20070129566-A1 | FLUOROADAMANTANE DERIVATIVE | ASAHI GLASS COMPANY, LIMITED (JP) | 2007-06-07 | — | — | US | disclosed |
| EP-1757575-A1 | FLUOROADAMANTANE DERIVATIVE | Asahi Glass Company, Limited (JP) | 2007-02-28 | — | — | EP | disclosed |
| US-20050288528-A1 | Fluorinated adamantane and its derivatives | ASAHI GLASS COMPANY LIMITED (JP) | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288528-A1 | Fluorinated adamantane and its derivatives | ADH1A, AFF1, ADH5 | PKM 4795/4885 |
| US-20080132736-A1 | FLUOROADAMANTANE DERIVATIVE | AFF1, AFF2, AFF4 | PKM 3859/4885 |
| US-20070129566-A1 | FLUOROADAMANTANE DERIVATIVE | AFF1, AFF2, AFF4 | PKM 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.