SCHEMBL432308

SCHEMBL432308

c1ccc(Cc2ccncc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.67
LTA4H P09960 1/20 0.60
CYP11B1 P15538 3/20 0.57
CYP11B2 P19099 3/20 0.57
CYP3A4 P08684 4/20 0.54
CYP1A2 P05177 3/20 0.54
CYP2D6 P10635 3/20 0.54
CYP2C9 P11712 3/20 0.54
CYP2C19 P33261 3/20 0.54
HIF1A Q16665 1/20 0.54
CYP17A1 P05093 2/20 0.52
CYP19A1 P11511 2/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
SLC6A3 Q01959 1/20 0.52
LSS P48449 1/20 0.51
NOTUM Q6P988 1/20 0.50
S1PR1 P21453 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9512609 1.00 CALM1 (0.67) CALM1LTA4HCYP11B1CYP11B2CYP3A4
Bromide SCHEMBL21658864 0.97 CALM1 (0.63) CALM1LTA4HCYP11B1CYP11B2CYP3A4
Hydrochloric Acid SCHEMBL28806112 0.97 CALM1 (0.63) CALM1LTA4HCYP11B1CYP11B2CYP3A4
SCHEMBL29452943 0.97 CALM1 (0.63) CALM1LTA4HCYP11B1CYP11B2CYP3A4
Ammonia Solution, Strong SCHEMBL6000295 0.97 CALM1 (0.63) CALM1LTA4HCYP11B1CYP11B2CYP3A4
Diphenylmethane SCHEMBL27810624 0.89 CALM1 (0.67) CALM1LTA4HCYP11B1CYP11B2CYP3A4
SCHEMBL27680608 0.89 LTA4H (0.56) CALM1LTA4HCYP11B1CYP11B2CYP3A4
Selenium SCHEMBL10543351 0.89 LTA4H (0.56) CALM1LTA4HCYP11B1CYP11B2CYP3A4
SCHEMBL721736 0.88 CYP17A1 (0.61) CYP11B1CYP11B2CYP3A4CYP1A2CYP2D6
SCHEMBL13873567 0.85 CYP17A1 (0.65) CYP11B1CYP11B2CYP3A4CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 884 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4314945-B1 ELECTROCHROMIC ELEMENT, ELECTROCHROMIC DISPLAY DEVICE, ELECTROCHROMIC LIGHT-CONTROLLING DEVICE, AND ELECTROLYTE COMPOSITION RICOH CO LTD (JP) 2025-12-17 EP claimed
CN-119979129-A Cooling liquid, preparation method thereof, battery and power utilization device 宁德时代新能源科技股份有限公司 2025-05-13 CN claimed
CN-119932765-A Copper-iodine cluster-based thermochromic fluorescent fiber as well as wet spinning preparation method and application thereof 江南大学 2025-05-06 CN claimed
CN-119751857-A Non-isocyanate polyurea and preparation method thereof, water-based non-isocyanate polyurea and preparation method thereof, and anti-corrosion coating, waterproof coating and fireproof coating containing water-based non-isocyanate polyurea and preparation method thereof 山西省建筑科学研究院集团有限公司 2025-04-04 CN claimed
CN-118813261-A Silicon nitride etching solution suitable for deep trench etching 湖北兴福电子材料股份有限公司 2024-10-22 CN claimed
CN-112062956-B Polyimide elastic gel and preparation method and application thereof 北京化工大学 2024-03-01 CN claimed
CN-117285662-A Chitosan bipyridine quaternary ammonium salt and preparation method thereof 南京仁为医药科技有限公司 2023-12-26 CN claimed
CN-111961236-B Low-dielectric polyimide film and preparation method and application thereof 北京化工大学 2023-10-20 CN claimed
CN-113046056-B Quantum dot material, preparation method thereof, quantum dot light emitting diode and light emitting device TCL科技集团股份有限公司 2023-06-16 CN claimed
CN-115947665-A Synthetic method of alpha-aryl-beta-chloroamide 湘潭大学 2023-04-11 CN claimed
EP-0315149-A2 Process for the preparation of imidized acrylic polymers ELF ATOCHEM ITALIA S.r.l. (IT) 1989-05-10 EP claimed
EP-0315150-A2 Imidized acrylic polymers and process for the preparation thereof ELF ATOCHEM ITALIA S.r.l. (IT) 1989-05-10 EP claimed
EP-0275918-A2 Process for the preparation of imidized acrylic polymers ATOCHEM INDUSTRIALE s.r.l. (IT) 1988-07-27 EP claimed
US-4619861-A COATING PARTICLES WITH ORGANONITROGEN OR ORGANOSULFUR POLYMER TDK CORPORATION (JP) 1986-10-28 US claimed
US-4588833-A CARBON MONOXIDE, ALCOHOL OR AMINE, ACID, UNSATURATED AMIDE, COBALTCOMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1986-05-13 US claimed
US-4377691-A Process for the preparation of 1-(4-hydroxyphenyl)-2-(4-benzylpiperidino)-1-propanol and acid-addition salts thereof KABUSHIKI KAISHA COSMOS ENTERPRISE (JP) 1983-03-22 US claimed
US-4177349-A BY-PRODUCT INHIBITION REILLY TAR & CHEMICAL CORPORATION (US) 1979-12-04 US claimed
US-4009087-A N-HETERO AROMATIC, AND SULFOALKYL OR SULFOARYL SULFIDE M&T CHEMICALS INC. (US) 1977-02-22 US claimed
US-4005227-A SUBSTITUTED PYRIDINE, SOLUBLE COFFEE FIRMENICH & CIE (CH) 1977-01-25 US claimed
US-3947402-A CYCLODEHYDRATION OF POLYAMIDE CARBOXYLIC ACID IN PRESENCE OF NITROGEN COMPOUND DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1976-03-30 US claimed