SCHEMBL9512609

SCHEMBL9512609

c1ccc(Cc2ccncc2)cc1.c1ccc(Cc2ccncc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.67
LTA4H P09960 1/20 0.60
CYP11B1 P15538 3/20 0.57
CYP11B2 P19099 3/20 0.57
CYP3A4 P08684 4/20 0.54
CYP1A2 P05177 3/20 0.54
CYP2D6 P10635 3/20 0.54
CYP2C9 P11712 3/20 0.54
CYP2C19 P33261 3/20 0.54
HIF1A Q16665 1/20 0.54
CYP17A1 P05093 2/20 0.52
CYP19A1 P11511 2/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
SLC6A3 Q01959 1/20 0.52
LSS P48449 1/20 0.51
NOTUM Q6P988 1/20 0.50
S1PR1 P21453 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL432308 1.00 CALM1 (0.67) CALM1LTA4HCYP11B1CYP11B2CYP3A4
Bromide SCHEMBL21658864 0.97 CALM1 (0.63) CALM1LTA4HCYP11B1CYP11B2CYP3A4
Hydrochloric Acid SCHEMBL28806112 0.97 CALM1 (0.63) CALM1LTA4HCYP11B1CYP11B2CYP3A4
SCHEMBL29452943 0.97 CALM1 (0.63) CALM1LTA4HCYP11B1CYP11B2CYP3A4
Ammonia Solution, Strong SCHEMBL6000295 0.97 CALM1 (0.63) CALM1LTA4HCYP11B1CYP11B2CYP3A4
Diphenylmethane SCHEMBL27810624 0.89 CALM1 (0.67) CALM1LTA4HCYP11B1CYP11B2CYP3A4
SCHEMBL27680608 0.89 LTA4H (0.56) CALM1LTA4HCYP11B1CYP11B2CYP3A4
Selenium SCHEMBL10543351 0.89 LTA4H (0.56) CALM1LTA4HCYP11B1CYP11B2CYP3A4
SCHEMBL721736 0.88 CYP17A1 (0.61) CYP11B1CYP11B2CYP3A4CYP1A2CYP2D6
SCHEMBL13873567 0.85 CYP17A1 (0.65) CYP11B1CYP11B2CYP3A4CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0287956-B1 Process for the preparation of 5-formylevalerianic acid esters or the corresponding acetals BASF AG (DE) 1993-11-24 EP disclosed
EP-0287956-A2 Process for the preparation of 5-formylevalerianic acid esters or the corresponding acetals BASF Aktiengesellschaft (DE) 1988-10-26 EP disclosed