Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695232 | 0.83 | ELANE (0.54) | TDP1RAB9AALDH1A1HPGDPOLB | |
| SCHEMBL13343685 | 0.83 | ALDH1A1 (0.45) | HSP90AA1ESR2TDP1RAB9AALDH1A1 | |
| SCHEMBL8146154 | 0.81 | MAPT (0.55) | TDP1RAB9AALDH1A1SMN1; SMN2MAOA | |
| SCHEMBL12790422 | 0.80 | P2RY14 (0.58) | TDP1RAB9AALDH1A1HPGDPOLB | |
| SCHEMBL29243709 | 0.80 | ALDH1A1 (0.44) | HSP90AA1ESR2TDP1RAB9AALDH1A1 | |
| SCHEMBL5188247 | 0.79 | HPSE (0.58) | TDP1RAB9AALDH1A1HPGDPOLB | |
| SCHEMBL6816248 | 0.79 | ALDH1A1 (0.51) | HSP90AA1ESR2TDP1RAB9AALDH1A1 | |
| SCHEMBL6625442 | 0.78 | ALDH1A1 (0.43) | HSP90AA1ESR2TDP1RAB9AALDH1A1 | |
| SCHEMBL15764671 | 0.78 | RAB9A (0.83) | RAB9AALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL6816258 | 0.77 | MAPT (0.46) | RAB9AALDH1A1HPGDSMN1; SMN2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |