Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.83 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | MMP2 | P08253 | 3/20 | 0.60 |
| ▸ | MMP9 | P14780 | 3/20 | 0.60 |
| ▸ | MMP8 | P22894 | 3/20 | 0.60 |
| ▸ | MMP13 | P45452 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4325535 | 0.78 | HSP90AA1 (0.50) | RAB9AMAPTKMT2AMEN1POLB | |
| SCHEMBL4328210 | 0.77 | ALDH1A1 (0.58) | RAB9AMAPTMMP2MMP9MMP8 | |
| SCHEMBL14381553 | 0.77 | MMP2 (0.69) | RAB9AMAPTMMP2MMP9MMP8 | |
| SCHEMBL271133 | 0.77 | RAB9A (0.70) | RAB9AMAPTKMT2AMEN1POLB | |
| SCHEMBL8710971 | 0.77 | RAB9A (0.80) | RAB9AMAPTKMT2AMEN1POLB | |
| SCHEMBL12109610 | 0.77 | MAPT (0.57) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14381527 | 0.76 | MMP2 (0.68) | RAB9AMAPTMMP2MMP9MMP8 | |
| SCHEMBL14381566 | 0.76 | MMP2 (0.68) | RAB9AMAPTMMP2MMP9MMP8 | |
| SCHEMBL23898948 | 0.76 | KMT2A (0.83) | RAB9AMAPTKMT2AMEN1POLB | |
| SCHEMBL8572381 | 0.76 | KMT2A (0.83) | RAB9AMAPTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150191701-A1 | ENHANCERS OF INDUCED PLURIPOTENT STEM CELL REPROGRAMMING | CITY OF HOPE | 2015-07-09 | — | — | US | disclosed |
| US-8962322-B2 | Enhancers of induced pluripotent stem cell reprogramming | CITY OF HOPE | 2015-02-24 | — | — | US | disclosed |
| US-20140154805-A1 | ENHANCERS OF INDUCED PLURIPOTENT STEM CELL REPROGRAMMING | CITY OF HOPE (US) | 2014-06-05 | — | — | US | disclosed |