Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30195119 | 0.78 | MEN1 (0.54) | CYP1A2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL18694713 | 0.75 | TAS1R3 (0.47) | CYP1A2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3293927 | 0.75 | CYP1A2 (0.52) | CYP1A2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4639171 | 0.73 | MLYCD (0.52) | CYP1A2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL823146 | 0.72 | CYP1A2 (0.48) | CYP1A2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL12706055 | 0.71 | MEN1 (0.53) | MEN1KMT2AALDH1A1RAB9ALMNA | |
| SCHEMBL823157 | 0.71 | CYP1A2 (0.56) | CYP1A2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9511408 | 0.71 | CYP1A2 (0.39) | CYP1A2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8762296 | 0.70 | MEN1 (0.60) | MEN1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL27201021 | 0.69 | CYP1A2 (0.37) | CYP1A2MEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491989-B2 | Positive charging photoreceptor | XEROX CORPORATION (US) | 2009-02-17 | — | — | US | disclosed |
| EP-1640808-B1 | Photoconductive imaging members | XEROX CORP (US) | 2008-07-09 | — | — | EP | disclosed |
| US-7312007-B2 | Hole blocking layer containing a metal oxide (TiO2) having an aspect ratio of 4-5 and powder resistance of 1x104-6x104 ohm/cm when applied at a pressure of 650-50 kg/cm2 and a binder; photogenerating layer; and a charge transport layer | XEROX CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-20070023747-A1 | Positive charging photoreceptor | XEROX CORPORATION (US) | 2007-02-01 | — | — | US | disclosed |
| US-7070894-B2 | Photoconductive imaging members | XEROX CORPORATION (US) | 2006-07-04 | — | — | US | disclosed |
| US-20060057480-A1 | Photoconductive imaging members | XEROX CORPORATION | 2006-03-16 | — | — | US | disclosed |
| US-20050175913-A1 | Photoconductive imaging members | XEROX CORPORATION | 2005-08-11 | — | — | US | disclosed |
| US-6858363-B2 | Photoconductive imaging members | XEROX CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20040197686-A1 | Prevents, or minimizes dark injection, and wherein the resulting photoconducting members possess, for example, excellent photoinduced discharge characteristics, cyclic and environmental stability and acceptable charge deficient spot | XEROX CORPORATION | 2004-10-07 | — | — | US | disclosed |