Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CEL | P19835 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434608 | 0.98 | GAA (0.56) | GAATSHRAGTR1PTGDR2PTGDR | |
| SCHEMBL432356 | 0.96 | GAA (0.53) | GAATSHRAGTR1PTGDR2PTGDR | |
| SCHEMBL433540 | 0.91 | GAA (0.52) | GAATSHRAGTR1HTR2AHTR2C | |
| SCHEMBL3793544 | 0.84 | CHRNB2 (0.57) | GAATSHRAGTR1PTGDR2PTGDR | |
| SCHEMBL3795015 | 0.83 | CHRNB2 (0.55) | GAATSHRAGTR1PTGDR2PTGDR | |
| SCHEMBL15566598 | 0.83 | PTGDR2 (0.49) | GAATSHRAGTR1PTGDR2PTGDR | |
| Bicarbonate SCHEMBL17644450 | 0.82 | TSHR (0.49) | GAATSHRAGTR1PTGDR2PTGDR | |
| SCHEMBL3385674 | 0.82 | SLC6A2 (0.52) | GAATSHRAGTR1HTR2C | |
| SCHEMBL3785820 | 0.81 | SLC6A2 (0.51) | GAATSHRAGTR1CEL | |
| SCHEMBL126782 | 0.81 | PTGDR2 (0.50) | GAATSHRAGTR1PTGDR2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498717-A1 | COMPOSITION FOR HARDENING SOFT TISSUE | The Catholic University of Korea Industry-Academic Cooperation Foundation (KR) | 2019-06-19 | — | — | EP | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |