Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432639 | 0.96 | GAA (0.58) | GAATSHRAGTR1HTR2AHTR2C | |
| SCHEMBL434608 | 0.94 | GAA (0.56) | GAATSHRAGTR1HTR2AHTR2C | |
| SCHEMBL433540 | 0.91 | GAA (0.52) | GAATSHRAGTR1HTR2AHTR2C | |
| SCHEMBL3785706 | 0.84 | CHRNB2 (0.57) | GAATSHRAGTR1PTGDRPTGDR2 | |
| SCHEMBL3385674 | 0.82 | SLC6A2 (0.52) | GAATSHRAGTR1HTR2CCHRNB2 | |
| Bicarbonate SCHEMBL17644450 | 0.82 | TSHR (0.49) | GAATSHRAGTR1TP53PTGDR | |
| SCHEMBL3784884 | 0.81 | SLC6A2 (0.47) | GAATSHRAGTR1SIGMAR1TMEM97 | |
| Hydrochloric Acid SCHEMBL4886168 | 0.80 | SLC6A2 (0.51) | GAATSHRAGTR1HTR2AHTR2C | |
| SCHEMBL3793544 | 0.80 | CHRNB2 (0.57) | GAATSHRAGTR1PTGDRPTGDR2 | |
| SCHEMBL16455135 | 0.80 | HTR2A (0.52) | HTR2AHTR2CCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239861-A | Preparation method of 1- (2, 4-dichlorophenyl) -1-cyclopropanecarbonitrile | 山东京博农化科技股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-114163382-A | Cyclobutanamide compound or salt thereof acceptable as pesticide, composition and application thereof | 海利尔药业集团股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3558956-B1 | N-CYCLOBUTYL-THIAZOL-5-CARBOXAMIDES WITH NEMATICIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2020-10-28 | — | — | EP | disclosed |
| CN-105431414-B | The 4 round rings formamides as nematicide | 先正达参股股份有限公司 | 2018-06-15 | — | — | CN | disclosed |
| EP-3019476-B1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-17 | — | — | EP | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |