Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432797 | 0.86 | POLB (0.43) | ALDH1A1LMNAMAPTPIK3CDUSP30 | |
| SCHEMBL432686 | 0.85 | MYC (0.39) | MAPTTRPV1PIK3CDRORCGPR119 | |
| SCHEMBL433752 | 0.84 | TRPV1 (0.41) | TRPV1GPBAR1PIK3CDUSP30RORC | |
| SCHEMBL6113229 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTGPBAR1PIK3CD | |
| SCHEMBL462924 | 0.79 | GPR119 (0.39) | ALDH1A1LMNAMAPTPIK3CDGPR119 | |
| SCHEMBL30044261 | 0.79 | GPR119 (0.39) | ALDH1A1LMNAMAPTPIK3CDGPR119 | |
| SCHEMBL24792687 | 0.78 | PIK3CD (0.44) | ALDH1A1LMNAMAPTPIK3CDUSP30 | |
| SCHEMBL30045189 | 0.77 | CACNB4 (0.41) | ALDH1A1LMNAMAPTPIK3CDRORC | |
| SCHEMBL23580556 | 0.77 | CACNB4 (0.41) | ALDH1A1LMNAMAPTPIK3CDRORC | |
| SCHEMBL18615599 | 0.77 | MAPT (0.46) | ALDH1A1LMNAMAPTRORCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012366-A1 | PESTICIDAL 3-(ARYLOXY)AZACYCLOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |