Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.39 |
| ▸ | MAX | P61244 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432685 | 0.85 | ALDH1A1 (0.40) | GPR119PIK3CDRORCTRPV1MAPT | |
| SCHEMBL462925 | 0.80 | HDAC2 (0.36) | MYCMAXGPR119HDAC2PIK3CD | |
| SCHEMBL1937743 | 0.72 | TXNRD1 (0.39) | — | |
| SCHEMBL432797 | 0.72 | POLB (0.43) | GPR119PIK3CDMAPT | |
| SCHEMBL433752 | 0.69 | TRPV1 (0.41) | GPR119HDAC2PIK3CDRORCTRPV1 | |
| SCHEMBL6113229 | 0.68 | ALDH1A1 (0.44) | GPR119PIK3CDMAPT | |
| SCHEMBL19172446 | 0.68 | MAPT (0.46) | MAPTJAK2 | |
| SCHEMBL4397750 | 0.67 | GPR119 (0.43) | GPR119HRH3TRPV1MAPT | |
| SCHEMBL4649370 | 0.66 | MAPT (0.49) | MAPT | |
| SCHEMBL433502 | 0.65 | HDAC2 (0.42) | GPR119HDAC2PIK3CDKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012366-A1 | PESTICIDAL 3-(ARYLOXY)AZACYCLOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |