Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PPOX | P50336 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489680 | 0.91 | FFAR1 (0.44) | FFAR1MEN1TTRPPOXKMT2A | |
| SCHEMBL12646428 | 0.79 | EPHX2 (0.56) | KCNH2EPHX2MAPTLMNA | |
| SCHEMBL10368379 | 0.79 | FFAR1 (0.46) | FFAR1MEN1TTRPPOXKMT2A | |
| SCHEMBL10482181 | 0.78 | HTR2A (0.53) | FFAR1MEN1TTRPPOXKMT2A | |
| SCHEMBL11095176 | 0.76 | FFAR1 (0.65) | FFAR1MEN1TTRPPOXKMT2A | |
| SCHEMBL15384989 | 0.75 | HTR2A (0.59) | FFAR1MEN1TTRPPOXKMT2A | |
| SCHEMBL11014355 | 0.74 | FFAR1 (0.48) | FFAR1MEN1TTRPPOXKMT2A | |
| SCHEMBL10489722 | 0.74 | LMNA (0.53) | FFAR1MEN1TTRKMT2ATDP1 | |
| SCHEMBL10609119 | 0.73 | FFAR1 (0.46) | FFAR1MEN1TTRPPOXKMT2A | |
| SCHEMBL4823721 | 0.73 | FFAR1 (0.48) | FFAR1MEN1TTRPPOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039685-A2 | Heterobicyclic compounds as P38 inhibitors | Array Biopharma, Inc. (US) | 2009-03-25 | — | — | EP | claimed |
| US-4571255-A | Subsituted phenoxybenzisoxazole herbicides | PPG INDUSTRIES, INC. (US) | 1986-02-18 | — | — | US | claimed |
| US-4571255-A | Subsituted phenoxybenzisoxazole herbicides | PPG INDUSTRIES, INC. (US) | 1986-02-18 | — | — | US | disclosed |